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Identification of differentially expressed genes in CFS subjects by clinical or epidemiologic variables. |
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| Clinical or epidemiologic variable |
SAMa |
t-Testb (unequal variance) |
Wilcoxonb |
|
|
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| Type of fatigue onset (gradual or sudden) |
117 |
199 |
159 |
| Illness group (1 or 2) |
0 |
15 |
1 |
| Age (≤50 or >50 years) |
4 |
29 |
22 |
| Body mass index (<25 or >30) |
0 |
4 |
5 |
| No. of symptoms (4 or ≥6) |
0 |
0 |
0 |
| Duration of illness (≤10 or >10) |
6 |
19 |
10 |
|
a Number of genes for which false discovery rate (FDR) = 5% b Number of genes for which comparison yielded p < 0.01 c The 7 subjects with 5 symptoms (Table 1) were excluded from the analysis of data shown in Table 2. Analysis including these subjects into either group did not significantly affect the outcome. | |||
Whistler et al. Journal of Translational Medicine 2003 1:10 doi:10.1186/1479-5876-1-10 |
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