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Volume 10 Issue 1

Comment

Commentary   Open Access

Does the FDA have regulatory authority over adult autologous stem cell therapies? 21 CFR 1271 and the emperor's new clothes

Michael Freeman, Mitchell Fuerst Journal of Translational Medicine 2012, 10:60 (26 March 2012)

Abstract | Full text | PDF | PubMed

Commentary   Open Access Highly Accessed

The role of BRAF V600 mutation in melanoma

Paolo A Ascierto, John M Kirkwood, Jean-Jacques Grob, Ester Simeone, Antonio M Grimaldi, Michele Maio, Giuseppe Palmieri, Alessandro Testori, Francesco M Marincola, Nicola Mozzillo Journal of Translational Medicine 2012, 10:85 (3 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Commentary   Open Access

Stereotactic Ablative Radio Therapy (SABR) followed by immunotherapy a challenge for individualized treatment of metastatic solid tumours

Giuseppe V Masucci, Peter Wersäll, Rolf Kiessling, Andreas Lundqvist, Rolf Lewensohn Journal of Translational Medicine 2012, 10:104 (22 May 2012)

Abstract | Full text | PDF | PubMed

Commentary   Open Access

Tracking the impact of translational research in psychiatry: state of the art and perspectives

Rodrigo Machado-Vieira Journal of Translational Medicine 2012, 10:175 (28 August 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access Highly Accessed

The immune score as a new possible approach for the classification of cancer

Jérôme Galon, Franck Pagès, Francesco M Marincola, Magdalena Thurin, Giorgio Trinchieri, Bernard A Fox, Thomas F Gajewski, Paolo A Ascierto Journal of Translational Medicine 2012, 10:1 (3 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access Highly Accessed

Supporting the advancement of science: Open access publishing and the role of mandates

Lisa Phelps, Bernard A Fox, Francesco M Marincola Journal of Translational Medicine 2012, 10:13 (24 January 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

Introducing the nutrition & metabolism section of journal of translational medicine

Laura Soldati, Elena Dogliotti, Irene Camera, Annalisa Terranegra Journal of Translational Medicine 2012, 10:17 (30 January 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

Expanding the perspective of translational medicine: the value of observational data

Michael N Liebman, Francesco M Marincola Journal of Translational Medicine 2012, 10:61 (27 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access Highly Accessed

Toward integrative cancer immunotherapy: targeting the tumor microenvironment

Leisha A Emens, Samuel C Silverstein, Samir Khleif, Francesco M Marincola, Jérôme Galon Journal of Translational Medicine 2012, 10:70 (10 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access

Lean oncology: a new model for oncologists

Vincenzo Montesarchio, Antonio Grimaldi, Bernard A Fox, Antonio Rea, Francesco M Marincola, Paolo A Ascierto Journal of Translational Medicine 2012, 10:74 (25 April 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

New section in journal of translational medicine: patient-targeted molecular therapies

Adrian Bot, Francesco Chiappelli Journal of Translational Medicine 2012, 10:92 (15 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access

Introducing the medical bioinformatics in Journal of Translational Medicine

Samir K Brahmachari Journal of Translational Medicine 2012, 10:202 (26 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Open Access

Introducing the Cardiovascular, metabolic and lipoprotein translation section of journal of translational medicine

Nehal N Mehta Journal of Translational Medicine 2012, 10:203 (26 September 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

Tumor biobanks in translational medicine

Gerardo Botti, Renato Franco, Monica Cantile, Gennaro Ciliberto, Paolo Ascierto Journal of Translational Medicine 2012, 10:204 (2 October 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

Computational modeling and epidemiologic approaches: a new section of the journal of translational medicine

Michael N Liebman, Sabrina Molinaro Journal of Translational Medicine 2012, 10:210 (17 October 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access Highly Accessed

Opportunities and challenges of disease biomarkers: a new section in the journal of translational medicine

Xiangdong Wang, Peter A Ward Journal of Translational Medicine 2012, 10:220 (7 November 2012)

Abstract | Full text | PDF | PubMed

Editorial   Open Access

Food ingredients and supplements: is this the future?

Patrizia Riso, Laura Soldati Journal of Translational Medicine 2012, 10:227 (19 November 2012)

Abstract | Full text | PDF | PubMed

Review

Review   Open Access Highly Accessed

Oncolytic virotherapy in veterinary medicine: current status and future prospects for canine patients

Sandeep S Patil, Ivaylo Gentschev, Ingo Nolte, Gregory Ogilvie, Aladar A Szalay Journal of Translational Medicine 2012, 10:3 (4 January 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Cancers of unknown primary origin: current perspectives and future therapeutic strategies

Giulia Stella, Rebecca Senetta, Adele Cassenti, Margherita Ronco, Paola Cassoni Journal of Translational Medicine 2012, 10:12 (24 January 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Cellular therapies for treating pain associated with spinal cord injury

Lawrence Leung Journal of Translational Medicine 2012, 10:37 (6 March 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

NF-κB as potential target in the treatment of melanoma

Gabriele Madonna, Claudio Ullman, Giusy Gentilcore, Giuseppe Palmieri, Paolo Ascierto Journal of Translational Medicine 2012, 10:53 (20 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access Highly Accessed

Novel classes of non-coding RNAs and cancer

Jiri Sana, Petra Faltejskova, Marek Svoboda, Ondrej Slaby Journal of Translational Medicine 2012, 10:103 (21 May 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

MicroRNA manipulation in colorectal cancer cells: from laboratory to clinical application

Muhammad Imran Aslam, Maleene Patel, Baljit Singh, John Stuart Jameson, James Howard Pringle Journal of Translational Medicine 2012, 10:128 (20 June 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Exosome removal as a therapeutic adjuvant in cancer

Annette M Marleau, Chien-Shing Chen, James A Joyce, Richard H Tullis Journal of Translational Medicine 2012, 10:134 (27 June 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

A systematic review and meta-analysis of 235delC mutation of GJB2 gene

Jun Yao, Yajie Lu, Qinjun Wei, Xin Cao, Guangqian Xing Journal of Translational Medicine 2012, 10:136 (2 July 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Considerations in the development of circulating tumor cell technology for clinical use

David R Parkinson, Nicholas Dracopoli, Brenda Petty, Carolyn Compton, Massimo Cristofanilli, Albert Deisseroth, Daniel F Hayes, Gordon Kapke, Prasanna Kumar, Jerry SH Lee, Minetta C Liu, Robert McCormack, Stanislaw Mikulski, Larry Nagahara, Klaus Pantel, Sonia Pearson-White, Elizabeth A Punnoose, Lori T Roadcap, Andrew E Schade, Howard I Scher, Caroline C Sigman, Gary J Kelloff Journal of Translational Medicine 2012, 10:138 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: With a systematic review of recent articles

Hiroshi Yao, Toru Nabika Journal of Translational Medicine 2012, 10:139 (6 July 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines

Roberto S Accolla, Giovanna Tosi Journal of Translational Medicine 2012, 10:154 (31 July 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

Hepatitis C virus infection in the immunocompromised host: a complex scenario with variable clinical impact

Anna Zignego, Carlo Giannini, Laura Gragnani, Alessia Piluso, Elisa Fognani Journal of Translational Medicine 2012, 10:158 (3 August 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

A road map to Translational Medicine in Qatar and a model for the world

Francesco M Marincola, Javaid I Sheikh Journal of Translational Medicine 2012, 10:177 (29 August 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

TGF-β – an excellent servant but a bad master

Lenka Kubiczkova, Lenka Sedlarikova, Roman Hajek, Sabina Sevcikova Journal of Translational Medicine 2012, 10:183 (3 September 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Cancer classification using the Immunoscore: a worldwide task force

Jérôme Galon, Franck Pagès, Francesco M Marincola, Helen K Angell, Magdalena Thurin, Alessandro Lugli, Inti Zlobec, Anne Berger, Carlo Bifulco, Gerardo Botti, Fabiana Tatangelo, Cedrik M Britten, Sebastian Kreiter, Lotfi Chouchane, Paolo Delrio, Hartmann Arndt, Martin Asslaber, Michele Maio, Giuseppe V Masucci, Martin Mihm, Fernando Vidal-Vanaclocha, James P Allison, Sacha Gnjatic, Leif Hakansson, Christoph Huber, Harpreet Singh-Jasuja, Christian Ottensmeier, Heinz Zwierzina, Luigi Laghi, Fabio Grizzi et al. Journal of Translational Medicine 2012, 10:205 (3 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access

Future detection and monitoring of diabetes may entail analysis of both β-cell function and volume: How markers of β-cell loss may assist

Anita V Neutzsky-Wulff, Kim V Andreassen, Sara T Hjuler, Michael Feigh, Anne-Christine Bay-Jensen, Qinlong Zheng, Kim Henriksen, Morten A Karsdal Journal of Translational Medicine 2012, 10:214 (30 October 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Human conditions of insulin-like growth factor-I (IGF-I) deficiency

Juan E Puche, Inma Castilla-Cortázar Journal of Translational Medicine 2012, 10:224 (14 November 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Roles of microRNA on cancer cell metabolism

Bing Chen, Hongbin Li, Xiao Zeng, Pengbo Yang, Xinyu Liu, Xia Zhao, Shufang Liang Journal of Translational Medicine 2012, 10:228 (20 November 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Exogenous endothelial cells as accelerators of hematopoietic reconstitution

J Mizer, Thomas E Ichim, Doru T Alexandrescu, Constantin A Dasanu, Famela Ramos, Andrew Turner, Erik J Woods, Vladimir Bogin, Michael P Murphy, David Koos, Amit N Patel Journal of Translational Medicine 2012, 10:231 (21 November 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

IL-12 based gene therapy in veterinary medicine

Darja Pavlin, Maja Cemazar, Gregor Sersa, Natasa Tozon Journal of Translational Medicine 2012, 10:234 (21 November 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access Highly Accessed

Nerve growth factor: from the early discoveries to the potential clinical use

Luigi Aloe, Maria Rocco, Patrizia Bianchi, Luigi Manni Journal of Translational Medicine 2012, 10:239 (29 November 2012)

Abstract | Full text | PDF | PubMed

Review   Open Access

Opportunities and challenges of disease biomarkers: a new section in the journal of translational medicine

Xiangdong Wang, Peter A Ward Journal of Translational Medicine 2012, 10:240 (5 December 2012)

Abstract | Full text | PDF | PubMed

Research

Research   Open Access

Preventing intimal thickening of vein grafts in vein artery bypass using STAT-3 siRNA

Jiangbin Sun, Jinhua Zheng, Kaitelynne H Ling, Keyan Zhao, Zhongshang Xie, Bo Li, Tiance Wang, Zhicheng Zhu, Amit N Patel, Weiping Min, Kexiang Liu, Xiufen Zheng Journal of Translational Medicine 2012, 10:2 (4 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Effects of adjuvants on IgG subclasses elicited by virus-like Particles

Maria Luisa Visciano, Maria Tagliamonte, Maria Lina Tornesello, Franco M Buonaguro, Luigi Buonaguro Journal of Translational Medicine 2012, 10:4 (5 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

Jonathan M Street, Perdita E Barran, C Logan Mackay, Stefan Weidt, Craig Balmforth, Tim S Walsh, Rod TA Chalmers, David J Webb, James W Dear Journal of Translational Medicine 2012, 10:5 (5 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Comparison of acute versus convalescent stage high-sensitivity C-Reactive protein level in predicting clinical outcome after acute ischemic stroke and impact of erythropoietin

Kuo-Ho Yeh, Tzu-Hsien Tsai, Han-Tan Chai, Steve Leu, Sheng-Ying Chung, Sarah Chua, Yung-Lung Chen, Hung-Sheng Lin, Chun-Man Yuen, Hon-Kan Yip Journal of Translational Medicine 2012, 10:6 (5 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

c-KIT receptor expression is strictly associated with the biological behaviour of thyroid nodules

Sara Tomei, Chiara Mazzanti, Ivo Marchetti, Leonardo Rossi, Katia Zavaglia, Francesca Lessi, Alessandro Apollo, Paolo Aretini, Giancarlo Di Coscio, Generoso Bevilacqua Journal of Translational Medicine 2012, 10:7 (10 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1

Salvador Mena, María L Rodriguez, Angel Ortega, Sonia Priego, Elena Obrador, Miguel Asensi, Ignacio Petschen, Miguel Cerdá, Bob D Brown, José M Estrela Journal of Translational Medicine 2012, 10:8 (10 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Functional hyper-IL-6 from vaccinia virus-colonized tumors triggers platelet formation and helps to alleviate toxicity of mitomycin C enhanced virus therapy

Julia B Sturm, Michael Hess, Stephanie Weibel, Nanhai G Chen, Yong A Yu, Qian Zhang, Ulrike Donat, Cora Reiss, Stepan Gambaryan, Georg Krohne, Jochen Stritzker, Aladar A Szalay Journal of Translational Medicine 2012, 10:9 (11 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy

George Fountzilas, Christos Valavanis, Vassiliki Kotoula, Anastasia G Eleftheraki, Konstantine T Kalogeras, Olympia Tzaida, Anna Batistatou, Ralf Kronenwett, Ralph M Wirtz, Mattheos Bobos, Eleni Timotheadou, Nikolaos Soupos, George Pentheroudakis, Helen Gogas, Dimitrios Vlachodimitropoulos, Genovefa Polychronidou, Gerasimos Aravantinos, Angelos Koutras, Christos Christodoulou, Dimitrios Pectasides, Petroula Arapantoni Journal of Translational Medicine 2012, 10:10 (12 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Suppression of zinc finger protein 467 alleviates osteoporosis through promoting differentiation of adipose derived stem cells to osteoblasts

Li You, Ling Pan, Lin Chen, Jin-Yu Chen, Xiaoping Zhang, Zhongwei Lv, Da Fu Journal of Translational Medicine 2012, 10:11 (17 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Perioperative dynamic alterations in peripheral regulatory T and B cells in patients with hepatocellular carcinoma

Tianxiang Chen, Dongli Song, Zhihui Min, Xiangdong Wang, Yu Gu, Bajin Wei, Jia Yao, Kangjie Chen, Zhijun Jiang, Haiyang Xie, Lin Zhou, Shusen Zheng Journal of Translational Medicine 2012, 10:14 (25 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Specifically targeting ERK1 or ERK2 kills Melanoma cells

Jianzhong Qin, Hong Xin, Brian J Nickoloff Journal of Translational Medicine 2012, 10:15 (25 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Prognostic effects of 25-hydroxyvitamin D levels in gastric cancer

Chao Ren, Miao-zhen Qiu, De-shen Wang, Hui-yan Luo, Dong-sheng Zhang, Zhi-qiang Wang, Feng-hua Wang, Yu-hong Li, Zhi-wei Zhou, Rui-hua Xu Journal of Translational Medicine 2012, 10:16 (27 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia

Pietro Bulian, Davide Rossi, Francesco Forconi, Giovanni Del Poeta, Francesco Bertoni, Emanuele Zucca, Marco Montillo, Gabriele Pozzato, Giovanni D'Arena, Dimitar G Efremov, Roberto Marasca, Francesco Lauria, Gianluca Gaidano, Valter Gattei, Luca Laurenti Journal of Translational Medicine 2012, 10:18 (30 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis

Rong Li, Xiufen Zheng, Igor Popov, Xusheng Zhang, Hongmei Wang, Motohiko Suzuki, Rosalia De Necochea-Campion, Peter W French, Di Chen, Leo Siu, David Koos, Robert D Inman, Wei-Ping Min Journal of Translational Medicine 2012, 10:19 (31 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Trend of transfusion transmitted infections frequency in blood donors: provide a road map for its prevention and control

Sobia Attaullah, Sanaullah Khan, Jabbar Khan Journal of Translational Medicine 2012, 10:20 (31 January 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC)

Zhuang-hua Li, Miao-zhen Qiu, Zhao-lei Zeng, Hui-yan Luo, Wen-jing Wu, Feng Wang, Zhi-qiang Wang, Dong-sheng Zhang, Yu-hong Li, Rui-hua Xu Journal of Translational Medicine 2012, 10:21 (3 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Validation of a single-platform, volumetric, flow cytometry for CD4 T cell count monitoring in therapeutic mobile unit

François-Xavier Mbopi-Kéou, Bertrand Sagnia, Jeanne Ngogang, Fru F Angwafo III, Vittorio Colizzi, Luc Montagnier, Laurent Bélec Journal of Translational Medicine 2012, 10:22 (6 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Sensitive and rapid quantification of C-reactive protein using quantum dot-labeled microplate immunoassay

Yang Luo, Bo Zhang, Ming Chen, Tianlun Jiang, Daiyang Zhou, Junfu Huang, Weiling Fu Journal of Translational Medicine 2012, 10:24 (6 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

The impact of IL28B genotype on the gene expression profile of patients with chronic hepatitis C treated with pegylated interferon alpha and ribavirin

Zobair M Younossi, Aybike Birerdinc, Mike Estep, Maria Stepanova, Arian Afendy, Ancha Baranova Journal of Translational Medicine 2012, 10:25 (7 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode

Qiong-Lin Liang, Xiao-Ping Liang, Yi-Ming Wang, Yuan-Yuan Xie, Rong-Li Zhang, Xi Chen, Rong Gao, Yi-Jun Cheng, Jun Wu, Qing-Bo Xu, Qing-Zhong Xiao, Xue Li, Shu-Feng Lv, Xue-Mei Fan, Hong-Yang Zhang, Qing-Li Zhang, Guo-An Luo Journal of Translational Medicine 2012, 10:26 (8 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Secreted protein acidic and rich in cysteine (SPARC) is associated with nasopharyngeal carcinoma metastasis and poor prognosis

Hai-Yun Wang, Yang-Yang Li, Qiong Shao, Jing-Hui Hou, Fang Wang, Man-Bo Cai, Yi-Xin Zeng, Jian-Yong Shao Journal of Translational Medicine 2012, 10:27 (9 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Phase I clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion

Erika Hamilton, Kimberly Blackwell, Amy C Hobeika, Timothy M Clay, Gloria Broadwater, Xiu-Rong Ren, Wei Chen, Henry Castro, Frederic Lehmann, Neil Spector, Junping Wei, Takuya Osada, H Kim Lyerly Journal of Translational Medicine 2012, 10:28 (10 February 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

PDCD6 is an independent predictor of progression free survival in epithelial ovarian cancer

Dan Su, Haiyan Xu, Jianguo Feng, Yun Gao, Linhui Gu, Lisha Ying, Dionyssios Katsaros, Herbert Yu, Shenhua Xu, Ming Qi Journal of Translational Medicine 2012, 10:31 (27 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Absolute lymphocyte count is associated with survival in ovarian cancer independent of tumor-infiltrating lymphocytes

Katy Milne, Cheryl Alexander, John R Webb, Winnie Sun, Kristy Dillon, Steve E Kalloger, C Blake Gilks, Blaise Clarke, Martin Köbel, Brad H Nelson Journal of Translational Medicine 2012, 10:33 (27 February 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Pharmacist counseling to cardiac patients in Israel prior to discharge from hospital contribute to increasing patient's medication adherence closing gaps and improving outcomes

Bishara Bisharat, Lubna Hafi, Orna Baron-Epel, Zaher Armaly, Abdalla Bowirrat Journal of Translational Medicine 2012, 10:34 (1 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Hyperglycemic conditions inhibit C3-mediated immunologic control of Staphylococcus aureus

Pamela S Hair, Charlene G Echague, Reuben D Rohn, Neel K Krishna, Julius O Nyalwidhe, Kenji M Cunnion Journal of Translational Medicine 2012, 10:35 (5 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR

Annette Håvik, Petter Brandal, Hilde Honne, Hanne-Sofie Dahlback, David Scheie, Merete Hektoen, Torstein Meling, Eirik Helseth, Sverre Heim, Ragnhild A Lothe, Guro Lind Journal of Translational Medicine 2012, 10:36 (6 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer

Kenny Chitcholtan, Peter H Sykes, John J Evans Journal of Translational Medicine 2012, 10:38 (6 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Translatability scoring in drug development: eight case studies

Alexandra Wendler, Martin Wehling Journal of Translational Medicine 2012, 10:39 (7 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Prostaglandin-induced cervical remodelling in humans in the first trimester is associated with increased expression of specific tight junction, but not gap junction proteins

Vidita V Ghulé, Colin Gray, Andrea Galimberti, Dilly OC Anumba Journal of Translational Medicine 2012, 10:40 (7 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Gene expression profiling of HCV genotype 3a initial liver fibrosis and cirrhosis patients using microarray

Waqar Ahmad, Bushra Ijaz, Sajida Hassan Journal of Translational Medicine 2012, 10:41 (7 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer

Xiwei Wu, George Somlo, Yang Yu, Melanie R Palomares, Arthur Li, Weiying Zhou, Amy Chow, Yun Yen, John J Rossi, Harry Gao, Jinhui Wang, Yate-Ching Yuan, Paul Frankel, Sierra Li, Kimlin Ashing-Giwa, Guihua Sun, Yafan Wang, Robin Smith, Kim Robinson, Xiubao Ren, Shizhen Wang Journal of Translational Medicine 2012, 10:42 (8 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Mitochondrial DNA mutation m.10680G > A is associated with Leber hereditary optic neuropathy in Chinese patients

A-Mei Zhang, Xiaoyun Jia, Xiangming Guo, Qingjiong Zhang, Yong-Gang Yao Journal of Translational Medicine 2012, 10:43 (9 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Developing a nanoparticle test for prostate cancer scoring

Qun Huo, Sally A Litherland, Shannon Sullivan, Hillari Hallquist, David A Decker, Inoel Rivera-Ramirez Journal of Translational Medicine 2012, 10:44 (9 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Performance of a multianalyte test as an aid for the diagnosis of ovarian cancer in symptomatic women

Dominic J Autelitano, Linda Raineri, Kate Knight, Kelly Bannister, Gregory E Rice Journal of Translational Medicine 2012, 10:45 (12 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Evaluation of cloned cells, animal model, and ATRA sensitivity of human testicular yolk sac tumor

Junfeng Zhao, Congde Chen, Haochuan Zhang, Jinhui Shen, Hua Zhang, Xiaokun Lin, Le Qin, Xiaozhou Bao, Jie Lin, Wenqiang Lu, Xiangdong Wang, Xiaoming Chen Journal of Translational Medicine 2012, 10:46 (13 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response

Stephen T Turner, Gary L Schwartz, Arlene B Chapman, Amber L Beitelshees, John G Gums, Rhonda M Cooper-DeHoff, Eric Boerwinkle, Julie A Johnson, Kent R Bailey Journal of Translational Medicine 2012, 10:47 (13 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer

David F Stroncek, Carolina Berger, Martin A Cheever, Richard W Childs, Mark E Dudley, Peter Flynn, Luca Gattinoni, James R Heath, Michael Kalos, Francesco M Marincola, Jeffrey S Miller, Gustavo Mostoslavsky, Daniel J Powell, Mahendra Rao, Nicholas P Restifo, Steven A Rosenberg, John O'Shea, Cornelis JM Melief Journal of Translational Medicine 2012, 10:48 (15 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Responses of human adipose-derived mesenchymal stem cells to chemical microenvironment of the intervertebral disc

Chengzhen Liang, Hao Li, Yiqing Tao, Xiaopeng Zhou, Fangcai Li, Gang Chen, Qixin Chen Journal of Translational Medicine 2012, 10:49 (16 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Are hepatic steatosis and carotid intima media thickness associated in obese patients with normal or slightly elevated gamma-glutamyl-transferase?

Giovanni Tarantino, Carmine Finelli, Annamaria Colao, Domenico Capone, Marianna Tarantino, Ernesto Grimaldi, Donato Chianese, Saverio Gioia, Fabrizio Pasanisi, Franco Contaldo, Francesco Scopacasa, Silvia Savastano Journal of Translational Medicine 2012, 10:50 (16 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Heterologous mesenchymal stem cells successfully treat femoral pseudarthrosis in rats

Manoel Ferreira, Paulo Silva, Lucas Alvarez Silva, Danielle Bonfim, Lucas Conilho Macedo Müller, Christiano Espósito, Alberto Schanaider Journal of Translational Medicine 2012, 10:51 (20 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Expression of chemokine receptors on circulating tumor cells in patients with solid tumors

Alberto Fusi, Zhian Liu, Verena Kümmerlen, Anika Nonnemacher, Judith Jeske, Ulrich Keilholz Journal of Translational Medicine 2012, 10:52 (20 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Suppression of ribosomal protein synthesis and protein translation factors by Peg-interferon alpha/ribavirin in HCV patients blood mononuclear cells (PBMC)

Rahul Gupta, Sun Kim, Milton W Taylor Journal of Translational Medicine 2012, 10:54 (22 March 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access Highly Accessed

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma

Martina Redova, Alexandr Poprach, Jana Nekvindova, Robert Iliev, Lenka Radova, Radek Lakomy, Marek Svoboda, Rostislav Vyzula, Ondrej Slaby Journal of Translational Medicine 2012, 10:55 (22 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide

Julio D Duarte, Issam Zineh, Ben Burkley, Yan Gong, Taimour Y Langaee, Stephen T Turner, Arlene B Chapman, Eric Boerwinkle, John G Gums, Rhonda M Cooper-DeHoff, Amber L Beitelshees, Kent R Bailey, Roger B Fillingim, Bruce C Kone, Julie A Johnson Journal of Translational Medicine 2012, 10:56 (22 March 2012)

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Further evidence for the existence of major susceptibility of nasopharyngeal carcinoma in the region near HLA-A locus in Southern Chinese

Manli Zhao, Hongbing Cai, Xin Li, Hang Zheng, Xuexi Yang, Weiyi Fang, Longcheng Zhang, Ganguan Wei, Ming Li, Kaitai Yao, Xin Li Journal of Translational Medicine 2012, 10:57 (22 March 2012)

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Safety and feasibility of countering neurological impairment by intravenous administration of autologous cord blood in cerebral palsy

Young-Ho Lee, Kyung Choi, Jin Moon, Hyun-Joo Jun, Hye-Ryeong Kang, Se-In Oh, Hyung Kim, Jang Um, Mi Kim, Yun Choi, Young-Jun Lee, Hee-Jin Kim, Jong-Hwa Lee, Su Son, Soo-Jin Choi, Wonil Oh, Yoon-Sun Yang Journal of Translational Medicine 2012, 10:58 (23 March 2012)

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Erectile properties of the Rho-kinase inhibitor SAR407899 in diabetic animals and human isolated corpora cavernosa

Fabio Guagnini, Mara Ferazzini, Marco Grasso, Salvatore Blanco, Tiziano Croci Journal of Translational Medicine 2012, 10:59 (23 March 2012)

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Dietary habits in women with recurrent idiopathic calcium nephrolithiasis

Tiziana Meschi, Antonio Nouvenne, Andrea Ticinesi, Beatrice Prati, Angela Guerra, Franca Allegri, Federica Pigna, Laura Soldati, Giuseppe Vezzoli, Giovanni Gambaro, Fulvio Lauretani, Marcello Maggio, Loris Borghi Journal of Translational Medicine 2012, 10:63 (28 March 2012)

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Expression TGM2 and BNIP3 have prognostic significance in laryngeal cancer patients receiving surgery and postoperative radiotherapy: A retrospective study

Ting Jin, Huan-Xin Lin, Hui Lin, Li-Bing Guo, Nan Ge, Xiu-Yu Cai, Rui Sun, Wen-Kuan Chen, Qiu-Li Li, Wei-Han Hu Journal of Translational Medicine 2012, 10:64 (30 March 2012)

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Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis

Bing Pan, Hui Ren, Xiaofeng Lv, Yangyu Zhao, Baoqi Yu, Yubin He, Yijing Ma, Chenguang Niu, Jinge Kong, Fangzhu Yu, Wen-bing Sun, Youyi Zhang, Belinda Willard, Lemin Zheng Journal of Translational Medicine 2012, 10:65 (30 March 2012)

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The effect of bone marrow microenvironment on the functional properties of the therapeutic bone marrow-derived cells in patients with acute myocardial infarction

Johanna A Miettinen, Riikka J Salonen, Kari Ylitalo, Matti Niemelä, Kari Kervinen, Marjaana Säily, Pirjo Koistinen, Eeva-Riitta Savolainen, Timo H Mäkikallio, Heikki V Huikuri, Petri Lehenkari Journal of Translational Medicine 2012, 10:66 (2 April 2012)

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Ca2+-regulatory proteins in cardiomyocytes from the right ventricle in children with congenital heart disease

Yihe Wu, Wei Feng, Hao Zhang, Shoujun Li, De Wang, Xiangbin Pan, Shengshou Hu Journal of Translational Medicine 2012, 10:67 (2 April 2012)

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Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells

Eileen L Heinrich, Wendy Lee, Jianming Lu, Andrew M Lowy, Joseph Kim Journal of Translational Medicine 2012, 10:68 (2 April 2012)

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Phosphorylated AKT and MAPK expression in primary tumours and in corresponding metastases and clinical outcome in colorectal cancer patients receiving irinotecan-cetuximab

Mario Scartozzi, Riccardo Giampieri, Elena Maccaroni, Alessandra Mandolesi, Simona Biagetti, Simona Alfonsi, Lucio Giustini, Cristian Loretelli, Luca Faloppi, Alessandro Bittoni, Maristella Bianconi, Michela Del Prete, Italo Bearzi, Stefano Cascinu Journal of Translational Medicine 2012, 10:71 (10 April 2012)

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Skp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma

Yi Liang, Xue Hou, Qian Cui, Tie-Bang Kang, Jian-Hua Fu, Lan-Jun Zhang, Rong-Zhen Luo, Jie-Hua He, Yi-Xin Zeng, Hao-Xian Yang Journal of Translational Medicine 2012, 10:73 (25 April 2012)

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Nitric oxide augments mesenchymal stem cell ability to repair liver fibrosis

Gibran Ali, Sadia Mohsin, Mohsin Khan, Ghazanfar Nasir, Sulaiman Shams, Shaheen N Khan, Sheikh Riazuddin Journal of Translational Medicine 2012, 10:75 (25 April 2012)

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Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene

Tina Trdan Lušin, Bruno Stieger, Janja Marc, Aleš Mrhar, Jurij Trontelj, Andrej Zavratnik, Barbara Ostanek Journal of Translational Medicine 2012, 10:76 (25 April 2012)

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Prognostic significance of MyD88 expression by human epithelial ovarian carcinoma cells

Yi Zhu, Jian-Ming Huang, Guo-Nan Zhang, Xiao Zha, Bi-Fang Deng Journal of Translational Medicine 2012, 10:77 (25 April 2012)

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Nuclear overexpression of metastasis-associated protein 1 correlates significantly with poor survival in nasopharyngeal carcinoma

Wen-Fei Li, Na Liu, Rui-Xue Cui, Qing-Mei He, Mo Chen, Ning Jiang, Ying Sun, Jing Zeng, Li-Zhi Liu, Jun Ma Journal of Translational Medicine 2012, 10:78 (26 April 2012)

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Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study

Charles Kunos, Tomas Radivoyevitch, Fadi W Abdul-Karim, James Fanning, Ovadia Abulafia, Albert J Bonebrake, Lydia Usha Journal of Translational Medicine 2012, 10:79 (27 April 2012)

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Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage

Ryosuke Echigo, Nobuyuki Shimohata, Kensuke Karatsu, Fumiko Yano, Yuko Kayasuga-Kariya, Ayano Fujisawa, Takayo Ohto, Yoshihiro Kita, Motonao Nakamura, Shigeki Suzuki, Manabu Mochizuki, Takao Shimizu, Ung-il Chung, Nobuo Sasaki Journal of Translational Medicine 2012, 10:80 (30 April 2012)

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Molecular target based combinational therapeutic approaches in thyroid cancer

Shilpi Rajoria, Robert Suriano, Andrea L George, Ameet Kamat, Stimson P Schantz, Jan Geliebter, Raj K Tiwari Journal of Translational Medicine 2012, 10:81 (1 May 2012)

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SLC26A4 gene copy number variations in Chinese patients with non-syndromic enlarged vestibular aqueduct

Jiandong Zhao, Yongyi Yuan, Jing Chen, Shasha Huang, Guojian Wang, Dongyi Han, Pu Dai Journal of Translational Medicine 2012, 10:82 (2 May 2012)

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CD20-negative de novo diffuse large B-cell lymphoma in HIV-negative patients: A matched case-control analysis in a single institution

Ya-Jun Li, Zhi-Ming Li, Hui-Lan Rao, Yi Xia, Hui-Qiang Huang, Zhong-Jun Xia, Su Li, Wen-Yu Li, Wen-Qi Jiang Journal of Translational Medicine 2012, 10:84 (3 May 2012)

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Impact of obesity control on circulating level of endothelial progenitor cells and angiogenesis in response to ischemic stimulation

Yung-Lung Chen, Chia-Lo Chang, Cheuk-Kwan Sun, Chiung-Jen Wu, Tzu-Hsien Tsai, Sheng-Ying Chung, Sarah Chua, Kuo-Ho Yeh, Steve Leu, Jiunn-Jye Sheu, Fan-Yen Lee, Chia-Hung Yen, Hon-Kan Yip Journal of Translational Medicine 2012, 10:86 (8 May 2012)

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Predictive role of multiple gene alterations in response to cetuximab in metastatic colorectal cancer: A single center study

Paola Ulivi, Laura Capelli, Martina Valgiusti, Wainer Zoli, Emanuela Scarpi, Elisa Chiadini, Paola Rosetti, Sara Bravaccini, Daniele Calistri, Luca Saragoni, Andrea Casadei Gardini, Angela Ragazzini, Giovanni Frassineti, Dino Amadori, Alessandro Passardi Journal of Translational Medicine 2012, 10:87 (8 May 2012)

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Longitudinal investigation of natural killer cells and cytokines in chronic fatigue syndrome/myalgic encephalomyelitis

Ekua W Brenu, Mieke L van Driel, Donald R Staines, Kevin J Ashton, Sharni L Hardcastle, James Keane, Lotti Tajouri, Daniel Peterson, Sandra B Ramos, Sonya M Marshall-Gradisnik Journal of Translational Medicine 2012, 10:88 (9 May 2012)

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The application of observational data in translational medicine: analyzing tobacco-use behaviors of adolescents

Valeria Siciliano, Annalisa Pitino, Mercedes Gori, Olivia Curzio, Loredana Fortunato, Michael Liebman, Sabrina Molinaro Journal of Translational Medicine 2012, 10:89 (14 May 2012)

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A retrospective pooled analysis of response patterns and risk factors in recurrent malignant glioma patients receiving a nitrosourea-based chemotherapy

Alessandro Paccapelo, Ivan Lolli, Maria Fabrini, Giovanni Silvano, Beatrice Detti, Franco Perrone, Giuseppina Savio, Matteo Santoni, Erminio Bonizzoni, Tania Perrone, Silvia Scoccianti Journal of Translational Medicine 2012, 10:90 (14 May 2012)

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Increased HOX C13 expression in metastatic melanoma progression

Monica Cantile, Giosuè Scognamiglio, Annamaria Anniciello, Marisa Farina, Giusy Gentilcore, Clemente Santonastaso, Franco Fulciniti, Clemente Cillo, Renato Franco, Paolo A Ascierto, Gerardo Botti Journal of Translational Medicine 2012, 10:91 (14 May 2012)

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FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway

Chang-Han Chen, Li-Yen Shiu, Li-Jen Su, Chi-Ying F Huang, Shun-Chen Huang, Chao-Cheng Huang, Yu-Fang Yin, Wei-Sheng Wang, Hsin-Ting Tsai, Fu-Min Fang, Wan-Chu Chuang, Hong-Chang Kang, Chung-Feng Hwang Journal of Translational Medicine 2012, 10:93 (16 May 2012)

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Effects of combined antiretroviral therapy on B- and T-cell release from production sites in long-term treated HIV-1+ patients

Eugenia Quiros-Roldan, Federico Serana, Marco Chiarini, Cinzia Zanotti, Alessandra Sottini, Daria Gotti, Carlo Torti, Luigi Caimi, Luisa Imberti Journal of Translational Medicine 2012, 10:94 (16 May 2012)

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Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation

Sucheta Telang, Brian F Clem, Alden C Klarer, Amy L Clem, John O Trent, Richard Bucala, Jason Chesney Journal of Translational Medicine 2012, 10:95 (16 May 2012)

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Expression of heat shock protein 70 in nasopharyngeal carcinomas: different expression patterns correlate with distinct clinical prognosis

Man-Bo Cai, Xiao-Pai Wang, Jia-Xing Zhang, Hui-Qiong Han, Chao-Chun Liu, Jin-Xin Bei, Ruo-Jun Peng, Yi Liang, Qi-Sheng Feng, Hai-Yun Wang, Li-Zhen Chen, Sha Fu, Tiebang Kang, Jian-Yong Shao, Yi-Xin Zeng Journal of Translational Medicine 2012, 10:96 (16 May 2012)

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The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer

Hiroko Natsume, Kazuya Shinmura, Hong Tao, Hisaki Igarashi, Masaya Suzuki, Kiyoko Nagura, Masanori Goto, Hidetaka Yamada, Matsuyoshi Maeda, Hiroyuki Konno, Satoki Nakamura, Haruhiko Sugimura Journal of Translational Medicine 2012, 10:97 (16 May 2012)

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Cryopreservation of human vascular umbilical cord cells under good manufacturing practice conditions for future cell banks

Bianca Polchow, Kati Kebbel, Gerno Schmiedeknecht, Anne Reichardt, Wolfgang Henrich, Roland Hetzer, Cora Lueders Journal of Translational Medicine 2012, 10:98 (16 May 2012)

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Clinical use of Dieletrophoresis separation for live Adipose derived stem cells

Allan Y Wu, David M Morrow Journal of Translational Medicine 2012, 10:99 (17 May 2012)

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Treatment of one case of cerebral palsy combined with posterior visual pathway injury using autologous bone marrow mesenchymal stem cells

Min Li, Aixue Yu, Fangfang Zhang, GuangHui Dai, Hongbin Cheng, Xiaodong Wang, Yihua An Journal of Translational Medicine 2012, 10:100 (18 May 2012)

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Enhanced antitumoral efficacy and immune response following conditionally replicative adenovirus containing constitutive HSF1 delivery to rodent tumors

Rong Fan, Cheng Wang, Yang Wang, Ping Ren, Pingping Gan, Hui Ji, Zian Xia, Suiyu Hu, Qiongyao Zeng, Wei Huang, Yebin Jiang, Xi Huang Journal of Translational Medicine 2012, 10:101 (21 May 2012)

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Beneficial effects of non-matched allogeneic cord blood mononuclear cells upon patients with idiopathic osteoporosis

Jun Li, Li Zhang, Liang Zhou, Zheng-Ping Yu, Feng Qi, Bei Liu, Su-Xia Zi, Li Li, Yi Li, San-Bin Wang, Zheng-Jiang Cui, Xing-Hua Pan Journal of Translational Medicine 2012, 10:102 (21 May 2012)

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Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis

Yan Huang, Lin-Zi Li, Chris Zhang, Chun Yi, Li-Li Liu, Xuan Zhou, Guo-Bing Xie, Mu-Yan Cai, Yan Li, Jing-Ping Yun Journal of Translational Medicine 2012, 10:106 (24 May 2012)

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Sequencing of BRAF inhibitors and ipilimumab in patients with metastatic melanoma: a possible algorithm for clinical use

Paolo A Ascierto, Ester Simeone, Diana Giannarelli, Antonio M Grimaldi, Anna Romano, Nicola Mozzillo Journal of Translational Medicine 2012, 10:107 (28 May 2012)

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Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines

Sebastian Gnosa, Yang-Mei Shen, Chao-Jie Wang, Hong Zhang, Johannes Stratmann, Gunnar Arbman, Xiao-Feng Sun Journal of Translational Medicine 2012, 10:109 (29 May 2012)

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High expression of p300 is linked to aggressive features and poor prognosis of Nasopharyngeal Carcinoma

Zhi-Wei Liao, Tong-Chong Zhou, Xiao-Jun Tan, Xian-Lu Song, Yuan Liu, Xing-Yuan Shi, Wen-Jin Huang, Li-Li Du, Bo-Jun Tu, Xiao-dan Lin Journal of Translational Medicine 2012, 10:110 (30 May 2012)

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Effects of molecular structural variants on serum Krebs von den Lungen-6 levels in sarcoidosis

Masahiko Shigemura, Yasuyuki Nasuhara, Satoshi Konno, Chikara Shimizu, Kazuhiko Matsuno, Etsuro Yamaguchi, Masaharu Nishimura Journal of Translational Medicine 2012, 10:111 (31 May 2012)

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Racial differences in B cell receptor signaling pathway activation

Diane M Longo, Brent Louie, Kavita Mathi, Zoltan Pos, Ena Wang, Rachael E Hawtin, Francesco M Marincola, Alessandra Cesano Journal of Translational Medicine 2012, 10:113 (6 June 2012)

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Serum calcium level is related to both intima-media thickness and carotid atherosclerosis: a neglect risk factor in obese/overweight subjects

Tiziana Montalcini, Gaetano Gorgone, Arturo Pujia Journal of Translational Medicine 2012, 10:114 (6 June 2012)

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Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

Mark Rosenberg, Matthias Lutz, Constantin Kühl, Rainer Will, Volker Eckstein, Jutta Krebs, Hugo A Katus, Norbert Frey Journal of Translational Medicine 2012, 10:115 (6 June 2012)

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JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

Vladan P Cokic, Bhaskar Bhattacharya, Bojana B Beleslin-Cokic, Constance T Noguchi, Raj K Puri, Alan N Schechter Journal of Translational Medicine 2012, 10:116 (7 June 2012)

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Preparation and characterization of silk fibroin as a biomaterial with potential for drug delivery

Hao Zhang, Ling-ling Li, Fang-yin Dai, Hao-hao Zhang, Bing Ni, Wei Zhou, Xia Yang, Yu-zhang Wu Journal of Translational Medicine 2012, 10:117 (7 June 2012)

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The Chinese medicine formula HB01 reduces choroidal neovascularization by regulating the expression of vascular endothelial growth factor

Ming Jin, Youhua Zhang, Lin Pan, Renhui Dou, Robert B Nussenblatt, Lai Wei Journal of Translational Medicine 2012, 10:118 (7 June 2012)

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High level of miR-221/222 confers increased cell invasion and poor prognosis in glioma

Chunzhi Zhang, Junxia Zhang, Jianwei Hao, Zhendong Shi, Yingyi Wang, Lei Han, Shizhu Yu, Yongping You, Tao Jiang, Jinhuan Wang, Meili Liu, Peiyu Pu, Chunsheng Kang Journal of Translational Medicine 2012, 10:119 (8 June 2012)

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Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress

Hai-Feng Zhang, Shuang-Lun Xie, Yang-Xin Chen, Jing-Ting Mai, Jing-Feng Wang, Wa-Li Zhu, Li-Guang Zhu Journal of Translational Medicine 2012, 10:120 (8 June 2012)

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Gene expression analysis of matched ovarian primary tumors and peritoneal metastasis

Joel A Malek, Alejandra Martinez, Eliane Mery, Gwenael Ferron, Ruby Huang, Christophe Raynaud, Eva Jouve, Jean-Paul Thiery, Denis Querleu, Arash Rafii Journal of Translational Medicine 2012, 10:121 (11 June 2012)

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Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates

Carmen Unzu, Sandra Hervás-Stubbs, Ana Sampedro, Itsaso Mauleón, Uxua Mancheño, Carlos Alfaro, Rafael de Salamanca, Alberto Benito, Stuart G Beattie, Harald Petry, Jesús Prieto, Ignacio Melero, Antonio Fontanellas Journal of Translational Medicine 2012, 10:122 (15 June 2012)

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The impact of laser ablation on optical soft tissue differentiation for tissue specific laser surgery-an experimental ex vivo study

Florian Stelzle, Ingo Terwey, Christian Knipfer, Werner Adler, Katja Tangermann-Gerk, Emeka Nkenke, Michael Schmidt Journal of Translational Medicine 2012, 10:123 (15 June 2012)

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A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial

Nehal N Mehta, Sean P Heffron, Parth N Patel, Jane Ferguson, Rachana D Shah, Christine C Hinkle, Parasuram Krishnamoorthy, Rhia Shah, Jennifer Tabita-Martinez, Karen Terembula, Stephen R Master, Michael R Rickels, Muredach P Reilly Journal of Translational Medicine 2012, 10:124 (18 June 2012)

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Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue

David J Monsma, Noel R Monks, David M Cherba, Dawna Dylewski, Emily Eugster, Hailey Jahn, Sujata Srikanth, Stephanie B Scott, Patrick J Richardson, Robin E Everts, Aleksandr Ishkin, Yuri Nikolsky, James H Resau, Robert Sigler, Brian J Nickoloff, Craig P Webb Journal of Translational Medicine 2012, 10:125 (18 June 2012)

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The detrimental danger of water-pipe (Hookah) transcends the hazardous consequences of general health to the driving behavior

Wafa Elias, Nimer Assy, Ibrahim Elias, Tomer Toledo, Mustafa Yassin, Abdalla Bowirrat Journal of Translational Medicine 2012, 10:126 (18 June 2012)

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T cell receptor (TCR)-transgenic CD8 lymphocytes rendered insensitive to transforming growth factor beta (TGFβ) signaling mediate superior tumor regression in an animal model of adoptive cell therapy

Jon G Quatromoni, Yue Wang, Dan D Vo, Lilah F Morris, Ali R Jazirehi, William McBride, Talal Chatila, Richard C Koya, James S Economou Journal of Translational Medicine 2012, 10:127 (19 June 2012)

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Plasma nuclear and mitochondrial DNA levels as predictors of outcome in severe sepsis patients in the emergency room

Chia-Te Kung, Sheng-Yuan Hsiao, Tsung-Cheng Tsai, Chih-Min Su, Wen-Neng Chang, Chi-Ren Huang, Hung-Chen Wang, Wei-Che Lin, Hsueh-Wen Chang, Yu-Jun Lin, Ben-Chung Cheng, Ben Su, Nai-Wen Tsai, Cheng-Hsien Lu Journal of Translational Medicine 2012, 10:130 (21 June 2012)

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Use of neoadjuvant electrochemotherapy to treat a large metastatic lesion of the cheek in a patient with melanoma

Nicola Mozzillo, Corrado Caracò, Stefano Mori, Gianluca Di Monta, Gerardo Botti, Paolo A Ascierto, Corradina Caracò, Luigi Aloj Journal of Translational Medicine 2012, 10:131 (22 June 2012)

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Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix

Maria Benevolo, Antonio Musio, Amina Vocaturo, Maria Donà, Francesca Rollo, Irene Terrenato, Mariantonia Carosi, Edoardo Pescarmona, Giuseppe Vocaturo, Marcella Mottolese Journal of Translational Medicine 2012, 10:132 (25 June 2012)

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Adipose derived mesenchymal stem cells transplantation via portal vein improves microcirculation and ameliorates liver fibrosis induced by CCl4 in rats

Yu Wang, Fan Lian, Jiaping Li, Wenzhe Fan, Hanshi Xu, Xiuyan Yang, Liuqin Liang, Wei Chen, Jianyong Yang Journal of Translational Medicine 2012, 10:133 (26 June 2012)

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High expression of high mobility group box 1 (hmgb1) predicts poor prognosis for hepatocellular carcinoma after curative hepatectomy

Furong Liu, Yaojun Zhang, Zhenwei Peng, Hengjun Gao, Li Xu, Minshan Chen Journal of Translational Medicine 2012, 10:135 (2 July 2012)

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Obesity suppresses circulating level and function of endothelial progenitor cells and heart function

Tzu-Hsien Tsai, Han-Tan Chai, Cheuk-Kwan Sun, Chia-Hung Yen, Steve Leu, Yung-Lung Chen, Sheng-Ying Chung, Sheung-Fat Ko, Hsueh-Wen Chang, Chiung-Jen Wu, Hon-Kan Yip Journal of Translational Medicine 2012, 10:137 (2 July 2012)

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Clinical evaluation of a matrix metalloproteinase-12 cleaved fragment of titin as a cardiovascular serological biomarker

Efstathios Vassiliadis, Lars M Rasmussen, Inger Byrjalsen, Dorthe Larsen, Rajiv Chaturvedi, Susanne Hosbond, Lotte Saabye, Axel CP Diederichsen, Federica Genovese, Kevin L Duffin, Qinlong Zheng, Xiaoliang Chen, Diana J Leeming, Claus Christiansen, Morten A Karsdal Journal of Translational Medicine 2012, 10:140 (6 July 2012)

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Multicenter, phase II clinical trial of cancer vaccination for advanced esophageal cancer with three peptides derived from novel cancer-testis antigens

Koji Kono, Hisae Iinuma, Yasunori Akutsu, Hiroaki Tanaka, Naoko Hayashi, Yasuto Uchikado, Tsuyoshi Noguchi, Hideki Fujii, Kota Okinaka, Ryoji Fukushima, Hisahiro Matsubara, Masaichi Ohira, Hideo Baba, Shoji Natsugoe, Seigou Kitano, Kazuyoshi Takeda, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura Journal of Translational Medicine 2012, 10:141 (9 July 2012)

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Metabolomic profiling in blood from umbilical cords of low birth weight newborns

Carmen Ivorra, Consuelo García-Vicent, Felipe Javier Chaves, Daniel Monleón, José Manuel Morales, Empar Lurbe Journal of Translational Medicine 2012, 10:142 (9 July 2012)

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Correlation between the functional impairment of bone marrow-derived circulating progenitor cells and the extend of coronary artery disease

Ilkay Bozdag-Turan, R Turan, Lylia Paranskaya, Nicole S Arsoy, C Turan, Ibrahim Akin, Stephan Kische, Jasmin Ortak, H Schneider, S Ludovicy, Tina Hermann, Giuseppe D’Ancona, Serkan Durdu, A Akar, Hueseyin Ince, Christoph A Nienaber Journal of Translational Medicine 2012, 10:143 (9 July 2012)

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Effect of obesity reduction on preservation of heart function and attenuation of left ventricular remodeling, oxidative stress and inflammation in obese mice

Hui-Ting Wang, Chu-Feng Liu, Tzu-Hsien Tsai, Yung-Lung Chen, Hsueh-Wen Chang, Ching-Yen Tsai, Steve Leu, Yen-Yi Zhen, Han-Tan Chai, Sheng-Ying Chung, Sarah Chua, Chia-Hung Yen, Hon-Kan Yip Journal of Translational Medicine 2012, 10:145 (11 July 2012)

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Biomarkers on melanoma patient T Cells associated with ipilimumab treatment

Wenshi Wang, Daohai Yu, Amod A Sarnaik, Bin Yu, Maclean Hall, Dawn Morelli, Yonghong Zhang, Xiuhua Zhao, Jeffrey S Weber Journal of Translational Medicine 2012, 10:146 (12 July 2012)

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Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy

Chia-Hung Yen, Cheuk-Kwan Sun, Steve Leu, Christopher Wallace, Yu-Chun Lin, Li-Teh Chang, Yung-Lung Chen, Tzu-Hsien Tsa, Ying-Hsien Kao, Pei-Lin Shao, Chi-Ying Hsieh, Yen-Ta Chen, Hon-Kan Yip Journal of Translational Medicine 2012, 10:147 (19 July 2012)

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Novel HER2 Aptamer Selectively Delivers Cytotoxic Drug to HER2-positive Breast Cancer Cells in Vitro

Zhe Liu, Jin-Hong Duan, Yong-Mei Song, Jie Ma, Feng-Dan Wang, Xin Lu, Xian-Da Yang Journal of Translational Medicine 2012, 10:148 (20 July 2012)

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Upregulation of SATB1 is associated with the development and progression of glioma

Sheng-Hua Chu, Yan-Bin Ma, Dong-Fu Feng, Hong Zhang, Zhi-An Zhu, Zhi-Qiang Li, Pu-Cha Jiang Journal of Translational Medicine 2012, 10:149 (28 July 2012)

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Prognostic significance of c-KIT in vulvar cancer: bringing this molecular marker from bench to bedside

Beatriz de Melo Maia, André Lavorato-Rocha, Iara Rodrigues, Glauco Baiocchi, Flávia Cestari, Monica Stiepcich, Ludmila Chinen, Kátia C Carvalho, Fernando Soares, Rafael Rocha Journal of Translational Medicine 2012, 10:150 (28 July 2012)

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Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection

Shashi Bala, Yaphet Tilahun, Odette Taha, Hawau Alao, Karen Kodys, Donna Catalano, Gyongyi Szabo Journal of Translational Medicine 2012, 10:151 (30 July 2012)

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Characterization of iNOS+ Neutrophil-like ring cell in tumor-bearing mice

Lauren P Virtuoso, Jamie L Harden, Paula Sotomayor, Wade J Sigurdson, Fuminobu Yoshimura, Nejat K Egilmez, Boris Minev, Mehmet O Kilinc Journal of Translational Medicine 2012, 10:152 (30 July 2012)

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Synthetic genistein derivatives as modulators of glycosaminoglycan storage

Anna Kloska, Magdalena Narajczyk, Joanna Jakóbkiewicz-Banecka, Grzegorz Grynkiewicz, Wiesław Szeja, Magdalena Gabig-Cimińska, Grzegorz Węgrzyn Journal of Translational Medicine 2012, 10:153 (30 July 2012)

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Serum microRNAs as biomarkers for recurrence in melanoma

Erica B Friedman, Shulian Shang, Eleazar de Miera, Jacob Fog, Maria Teilum, Michelle W Ma, Russell S Berman, Richard L Shapiro, Anna C Pavlick, Eva Hernando, Adam Baker, Yongzhao Shao, Iman Osman Journal of Translational Medicine 2012, 10:155 (2 August 2012)

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First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients

Neil L Berinstein, Mohan Karkada, Michael A Morse, John J Nemunaitis, Gurkamal Chatta, Howard Kaufman, Kunle Odunsi, Rita Nigam, Leeladhar Sammatur, Lisa D MacDonald, Genevieve M Weir, Marianne M Stanford, Marc Mansour Journal of Translational Medicine 2012, 10:156 (3 August 2012)

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A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer

Lana E Kandalaft, Daniel J Powell, George Coukos Journal of Translational Medicine 2012, 10:157 (3 August 2012)

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Effects of sildenafil and/or muscle derived stem cells on myocardial infarction

Judy SC Wang, Istvan Kovanecz, Dolores Vernet, Gaby Nolazco, George E Kopchok, Sheryl L Chow, Rodney A White, Nestor F Gonzalez-Cadavid Journal of Translational Medicine 2012, 10:159 (7 August 2012)

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Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients

Roi Cal, Oriol Juan-Babot, Vicenç Brossa, Santiago Roura, Carolina Gálvez-Montón, Manolo Portoles, Miguel Rivera, Juan Cinca, Lina Badimon, Vicenta Llorente-Cortés Journal of Translational Medicine 2012, 10:160 (8 August 2012)

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Molecular evidence for increased antitumor activity of gemcitabine in combination with a cyclin-dependent kinase inhibitor, P276-00 in pancreatic cancers

Maggie J Rathos, Kavita Joshi, Harshal Khanwalkar, Sonal M Manohar, Kalpana S Joshi Journal of Translational Medicine 2012, 10:161 (8 August 2012)

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Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response

Emery Salom, Manuel Penalver, Howard Homesley, Matthew Burrell, Audrey Garrett, Cary A Presant, James Rutledge, Michael Chernick, Allan Hallquist, Mathieu Perree Journal of Translational Medicine 2012, 10:162 (8 August 2012)

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Combination of cilostazol and clopidogrel attenuates Rat critical limb ischemia

Jiunn-Jye Sheu, Kun-Chen Lin, Ching-Yen Tsai, Tzu-Hsien Tsai, Steve Leu, Chia-Hung Yen, Yung-Lung Chen, Hsueh-Wen Chang, Cheuk-Kwan Sun, Sarah Chua, Jenq-Lin Yang, Hon-Kan Yip Journal of Translational Medicine 2012, 10:164 (16 August 2012)

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Soluble KIT correlates with clinical outcome in patients with metastatic breast cancer treated with sunitinib

Kiana Keyvanjah, Samuel E DePrimo, Charles S Harmon, Xin Huang, Kenneth A Kern, William Carley Journal of Translational Medicine 2012, 10:165 (16 August 2012)

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Genetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury

Zhenju Song, Chenling Yao, Jun Yin, Chaoyang Tong, Duming Zhu, Zhan Sun, Jinjun Jiang, Mian Shao, Yaping Zhang, Zhi Deng, Zhengang Tao, Si Sun, Chunxue Bai Journal of Translational Medicine 2012, 10:166 (17 August 2012)

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Oncolytic vaccinia virus GLV-1h68 strain shows enhanced replication in human breast cancer stem-like cells in comparison to breast cancer cells

Huiqiang Wang, Nanhai G Chen, Boris R Minev, Aladar A Szalay Journal of Translational Medicine 2012, 10:167 (17 August 2012)

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GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer

Huan Li, Ling Guo, Shu-Wei Chen, Xiao-Hui Zhao, Shi-Min Zhuang, Li-Ping Wang, Li-Bing Song, Ming Song Journal of Translational Medicine 2012, 10:168 (20 August 2012)

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Adoptive cell therapy with autologous tumor infiltrating lymphocytes and low-dose Interleukin-2 in metastatic melanoma patients

Eva Ellebaek, Trine Iversen, Niels Junker, Marco Donia, Lotte Engell-Noerregaard, Özcan Met, Lisbet Hölmich, Rikke Andersen, Sine Hadrup, Mads Andersen, Per thor Straten, Inge Svane Journal of Translational Medicine 2012, 10:169 (21 August 2012)

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IRF5 gene polymorphisms in melanoma

Lorenzo Uccellini, Valeria De Giorgi, Yingdong Zhao, Barbara Tumaini, Narnygerel Erdenebileg, Mark E Dudley, Sara Tomei, Davide Bedognetti, Maria Ascierto, Qiuzhen Liu, Richard Simon, Leah Kottyan, Kenneth M Kaufman, John B Harley, Ena Wang, Steven A Rosenberg, Francesco M Marincola Journal of Translational Medicine 2012, 10:170 (21 August 2012)

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Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients

Oskar Hallgren, Sara Rolandsson, Annika Andersson-Sjöland, Kristian Nihlberg, Elisabet Wieslander, Martina Kvist-Reimer, Magnus Dahlbäck, Leif Eriksson, Leif Bjermer, Jonas S Erjefält, Claes-Göran Löfdahl, Gunilla Westergren-Thorsson Journal of Translational Medicine 2012, 10:171 (22 August 2012)

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Analysis of in vitro secretion profiles from adipose-derived cell populations

Sinead P Blaber, Rebecca A Webster, Cameron J Hill, Edmond J Breen, Donald Kuah, Graham Vesey, Benjamin R Herbert Journal of Translational Medicine 2012, 10:172 (22 August 2012)

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Characterization of CDKN2A(p16) methylation and impact in colorectal cancer: systematic analysis using pyrosequencing

Michel P Bihl, Anja Foerster, Alessandro Lugli, Inti Zlobec Journal of Translational Medicine 2012, 10:173 (27 August 2012)

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Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury

Derrick E Fouts, Rembert Pieper, Sebastian Szpakowski, Hans Pohl, Susan Knoblach, Moo-Jin Suh, Shih-Ting Huang, Inger Ljungberg, Bruce M Sprague, Sarah K Lucas, Manolito Torralba, Karen E Nelson, Suzanne L Groah Journal of Translational Medicine 2012, 10:174 (28 August 2012)

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Prevalence and prevalence trends of transfusion transmissible infections among blood donors at four chinese regional blood centers between 2000 and 2010

Changqing Li, Xiaopu Xiao, Huimin Yin, Miao He, Jianping Li, Yudong Dai, Yongshui Fu, Jianmin Ge, Yonglin Yang, Yan Luan, Changzhou Lin, Hongxiang Zhao, Wuping Li Journal of Translational Medicine 2012, 10:176 (28 August 2012)

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Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia

Grazia Palomba, Maria Colombino, Antonio Contu, Bruno Massidda, Giovanni Baldino, Antonio Pazzola, MariaTeresa Ionta, Francesca Capelli, Vittorio Trova, Tito Sedda, Giovanni Sanna, Francesco Tanda, Mario Budroni, Sardinian Translational Oncology Group (STOG), Giuseppe Palmieri, Antonio Cossu Journal of Translational Medicine 2012, 10:178 (29 August 2012)

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BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs

Michele Carbone, Laura Ferris, Francine Baumann, Andrea Napolitano, Christopher A Lum, Erin G Flores, Giovanni Gaudino, Amy Powers, Peter Bryant-Greenwood, Thomas Krausz, Elizabeth Hyjek, Rachael Tate, Joseph Friedberg, Tracey Weigel, Harvey I Pass, Haining Yang Journal of Translational Medicine 2012, 10:179 (30 August 2012)

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The presence of melanocytic tumors can provide physicians with a visual marker to identify individuals who may carry germline BAP1 mutations and so are at higher risk of developing melanoma and mesothelioma.

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Trastuzumab anti-tumor efficacy in patient-derived esophageal squamous cell carcinoma xenograft (PDECX) mouse models

Xianhua Wu, Jingchuan Zhang, Ruheng Zhen, Jing Lv, Li Zheng, Xinying Su, Guanshan Zhu, Paul R Gavine, Songtao Xu, Shaohua Lu, Jun Hou, Yalan Liu, Chen Xu, Yunshan Tan, Liang Xie, Xiaolu Yin, Deming He, Qunsheng Ji, Yingyong Hou, Di Ge Journal of Translational Medicine 2012, 10:180 (30 August 2012)

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Prognostic relevance of melanoma antigen D1 expression in colorectal carcinoma

Zhao-lei Zeng, Wen-jing Wu, Jing Yang, Zhen-jie Tang, Dong-liang Chen, Miao-zhen Qiu, Hui-yan Luo, Zhi-qiang Wang, Ying Jin, De-shen Wang, Rui-hua Xu Journal of Translational Medicine 2012, 10:181 (31 August 2012)

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Hematopoietic stem cell transplantation induces immunologic tolerance in renal transplant patients via modulation of inflammatory and repair processes

Duojiao Wu, Guisheng Qi, Xuanchuan Wang, Ming Xu, Ruiming Rong, Xiangdong Wang, Tongyu Zhu Journal of Translational Medicine 2012, 10:182 (31 August 2012)

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HLA-E expression in cervical adenocarcinomas: association with improved long-term survival

Vivian M Spaans, Alexander AW Peters, Gert Fleuren, Ekaterina S Jordanova Journal of Translational Medicine 2012, 10:184 (4 September 2012)

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Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients

Luca Sigalotti, Alessia Covre, Elisabetta Fratta, Giulia Parisi, Paolo Sonego, Francesca Colizzi, Sandra Coral, Samuele Massarut, John M Kirkwood, Michele Maio Journal of Translational Medicine 2012, 10:185 (5 September 2012)

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Circulating miR-200c as a diagnostic and prognostic biomarker for gastric cancer

Manuel Valladares-Ayerbes, Margarita Reboredo, Vanessa Medina-Villaamil, Pilar Iglesias-Díaz, Maria Lorenzo-Patiño, Mar Haz, Isabel Santamarina, Moisés Blanco, Juan Fernández-Tajes, Maria Quindós, Alberto Carral, Angélica Figueroa, Luis Antón-Aparicio, Lourdes Calvo Journal of Translational Medicine 2012, 10:186 (6 September 2012)

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Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats

Dominik Linz, Mathias Hohl, Felix Mahfoud, Jan-Christian Reil, Wolfgang Linz, Thomas Hübschle, Hans-Paul Juretschke, Claudia Neumann-Häflin, Hartmut Rütten, Michael Böhm Journal of Translational Medicine 2012, 10:187 (10 September 2012)

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Telocytes in the urinary system

Yonghua Zheng, Tongyu Zhu, Miao Lin, Duojiao Wu, Xiangdong Wang Journal of Translational Medicine 2012, 10:188 (10 September 2012)

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Effect of high-dose intravenous vitamin C on inflammation in cancer patients

Nina Mikirova, Joseph Casciari, Andrea Rogers, Paul Taylor Journal of Translational Medicine 2012, 10:189 (11 September 2012)

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Development of a new humanized mouse model to study acute inflammatory arthritis

Alexander V Misharin, G Haines, Shawn Rose, Angelical K Gierut, Richard S Hotchkiss, Harris Perlman Journal of Translational Medicine 2012, 10:190 (13 September 2012)

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Cytokine expression profiles of immune imbalance in post-mononucleosis chronic fatigue

Gordon Broderick, Ben Z Katz, Henrique Fernandes, Mary Fletcher, Nancy Klimas, Frederick A Smith, Maurice RG O’Gorman, Suzanne D Vernon, Renee Taylor Journal of Translational Medicine 2012, 10:191 (13 September 2012)

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Phenotypes and clinical significance of circulating CD4+CD25+ regulatory T cells (Tregs) in patients with acute-on-chronic liver failure (ACLF)

Jiezuan Yang, Ping Yi, Li Wei, Zherong Xu, Yunbo Chen, Lingling Tang, Lanjuan Li Journal of Translational Medicine 2012, 10:193 (15 September 2012)

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Parvovirus B19V DNA contamination in Chinese plasma and plasma derivatives

Wei Zhang, Ling Ke, Li Changqing, Yan Zhang, Wuping Li Journal of Translational Medicine 2012, 10:194 (17 September 2012)

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Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis

Anne Sofie Siebuhr, Jianxia Wang, Morten Karsdal, Anne-C Bay-Jensen, Jin Y, Zheng Q Journal of Translational Medicine 2012, 10:195 (20 September 2012)

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Wnt/beta-catenin signaling in embryonic stem cell converted tumor cells

Xinrong Peng, Tao Liu, Ying Wang, Qiaoling Yan, Huajun Jin, Linfang Li, Qijun Qian, Mengchao Wu Journal of Translational Medicine 2012, 10:196 (20 September 2012)

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Preoperative Cyfra21-1 and SCC-Ag serum titers predict survival in patients with stage II esophageal squamous cell carcinoma

Xun Cao, Lin Zhang, Gui-Rong Feng, Juan Yang, Ruo-Yan Wang, Jun Li, Xiao-Min Zheng, Yu-Jing Han Journal of Translational Medicine 2012, 10:197 (21 September 2012)

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Four clinically utilized drugs were identified and validated for treatment of adrenocortical cancer using quantitative high-throughput screening

Naris Nilubol, Lisa Zhang, Min Shen, Ya-Qin Zhang, Mei He, Christopher P Austin, Electron Kebebew Journal of Translational Medicine 2012, 10:198 (21 September 2012)

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Five novel glucose-6-phosphate dehydrogenase deficiency haplotypes correlating with disease severity

Ashraf Dallol, Huda Banni, Mamdooh A Gari, Mohammed H Al-Qahtani, Adel M Abuzenadeh, Fatin Al-Sayes, Adeel G Chaudhary, Jeffrey Bidwell, Wael Kafienah Journal of Translational Medicine 2012, 10:199 (24 September 2012)

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Overexpression of FoxM1 is associated with tumor progression in patients with clear cell renal cell carcinoma

Yi-Jun Xue, Ri-Hai Xiao, Da-Zhi Long, Xiao-Feng Zou, Xiao-Ning Wang, Guo-Xi Zhang, Yuan-Hu Yuan, Geng-Qing Wu, Jun Yang, Yu-Ting Wu, Hui Xu, Fo-Lin Liu, Min Liu Journal of Translational Medicine 2012, 10:200 (24 September 2012)

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Effects of helium and air inhalation on the innate and early adaptive immune system in healthy volunteers ex vivo

Gezina TML Oei, Kirsten F Smit, Djai vd Vondervoort, Daniel Brevoord, Arjan Hoogendijk, Catharina W Wieland, Markus W Hollmann, Benedikt Preckel, Nina C Weber Journal of Translational Medicine 2012, 10:201 (24 September 2012)

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Changes in specialized blood vessels in lymph nodes and their role in cancer metastasis

Ser Yee Lee, Chao-Nan Qian, Aik Seng Ooi, Peiyi Chen, Hui Min Bernice Wong, Swe Swe Myint, Jing Chii Wong, Siok Gek Jacqueline Hwang, Khee Chee Soo Journal of Translational Medicine 2012, 10:206 (4 October 2012)

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Comparison of endometrial regenerative cells and bone marrow stromal cells

Huan Wang, Ping Jin, Marianna Sabatino, Jiaqiang Ren, Sara Civini, Vladimir Bogin, Thomas E Ichim, David F Stroncek Journal of Translational Medicine 2012, 10:207 (5 October 2012)

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Proteomics-based identification of haptoglobin as a favourable serum biomarker for predicting long-term response to splenectomy in patients with primary immune thrombocytopenia

Chao-Xu Zheng, Zhuang-Qi Ji, Long-Juan Zhang, Qiong Wen, Liu-Hua Chen, Jun-Feng Yu, Dong Zheng Journal of Translational Medicine 2012, 10:208 (7 October 2012)

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Epigenetic silencing of the 3p22 tumor suppressor DLEC1 by promoter CpG methylation in non-Hodgkin and Hodgkin lymphomas

Zhaohui Wang, Lili Li, Xianwei Su, Zifen Gao, Gopesh Srivastava, Paul G Murray, Richard Ambinder, Qian Tao Journal of Translational Medicine 2012, 10:209 (11 October 2012)

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Bax/Mcl-1 balance affects neutrophil survival in intermittent hypoxia and obstructive sleep apnea: effects of p38MAPK and ERK1/2 signaling

Larissa Dyugovskaya, Andrey Polyakov, Victoria Cohen-Kaplan, Peretz Lavie, Lena Lavie Journal of Translational Medicine 2012, 10:211 (22 October 2012)

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Topoisomerase II alpha gene amplification is a favorable prognostic factor in patients with HER2-positive metastatic breast cancer treated with trastuzumab

George Fountzilas, Christos Christodoulou, Mattheos Bobos, Vassiliki Kotoula, Anastasia G Eleftheraki, Ioannis Xanthakis, Anna Batistatou, George Pentheroudakis, Nikolaos Xiros, Irene Papaspirou, Anna Koumarianou, Pavlos Papakostas, Dimitrios Bafaloukos, Dimosthenis V Skarlos, Konstantine T Kalogeras Journal of Translational Medicine 2012, 10:212 (23 October 2012)

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A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition

Valentina Masola, Maurizio Onisto, Gianluigi Zaza, Antonio Lupo, Giovanni Gambaro Journal of Translational Medicine 2012, 10:213 (24 October 2012)

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Abnormal expression of GADD45B in human colorectal carcinoma

Lisha Wang, Xiuying Xiao, Dali Li, Yayun Chi, Ping Wei, Yiqin Wang, Shujuan Ni, Cong Tan, Xiaoyan Zhou, Xiang Du Journal of Translational Medicine 2012, 10:215 (30 October 2012)

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Poorly differentiated synovial sarcoma is associated with high expression of enhancer of zeste homologue 2 (EZH2)

Yi-Che Changchien, Péter Tátrai, Gergő Papp, Johanna Sápi, László Fónyad, Miklós Szendrői, Zsuzsanna Pápai, Zoltán Sápi Journal of Translational Medicine 2012, 10:216 (30 October 2012)

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Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

Ines Greco, Nicola Day, Joanna Riddoch-Contreras, Jane Reed, Hilkka Soininen, Iwona Kłoszewska, Magda Tsolaki, Bruno Vellas, Christian Spenger, Patrizia Mecocci, Lars-Olof Wahlund, Andrew Simmons, Julie Barnes, Simon Lovestone Journal of Translational Medicine 2012, 10:217 (31 October 2012)

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Of 25 biomarker candidates identified for Alzheimer's Disease using in silico literature mining, 5 have subsequently been reported to be altered in AD patients, supporting the use of this method to derive valid biomarker candidates.

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Ganglioside GD2-specific trifunctional surrogate antibody Surek demonstrates therapeutic activity in a mouse melanoma model

Peter Ruf, Beatrix Schäfer, Nina Eissler, Ralph Mocikat, Juergen Hess, Matthias Plöscher, Susanne Wosch, Ivonne Suckstorff, Christine Zehetmeier, Horst Lindhofer Journal of Translational Medicine 2012, 10:219 (7 November 2012)

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Low-pressure pulsed focused ultrasound with microbubbles promotes an anticancer immunological response

Hao-Li Liu, Han-Yi Hsieh, Li-An Lu, Chiao-Wen Kang, Ming-Fang Wu, Chun-Yen Lin Journal of Translational Medicine 2012, 10:221 (11 November 2012)

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Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients

Andreia de Albuquerque, Ilja Kubisch, Ulrich Stölzel, Dominikus Ernst, Joachim Boese-Landgraf, Georg Breier, Gudrun Stamminger, Nikos Fersis, Sepp Kaul Journal of Translational Medicine 2012, 10:222 (13 November 2012)

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A gender-related action of IFNbeta-therapy was found in multiple sclerosis

Ida Contasta, Rocco Totaro, Patrizia Pellegrini, Tiziana Del Beato, Antonio Carolei, Anna Maria Berghella Journal of Translational Medicine 2012, 10:223 (14 November 2012)

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Identification of SLC26A4 c.919-2A>G compound heterozygosity in hearing-impaired patients to improve genetic counseling

Qi Li, Qing-wen Zhu, Yong-yi Yuan, Sha-sha Huang, Dong-yi Han, De-liang Huang, Pu Dai Journal of Translational Medicine 2012, 10:225 (14 November 2012)

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Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer

Aleksandra Markiewicz, Tomasz Ahrends, Marzena Wełnicka-Jaśkiewicz, Barbara Seroczyńska, Jarosław Skokowski, Janusz Jaśkiewicz, Jolanta Szade, Wojciech Biernat, Anna J Żaczek Journal of Translational Medicine 2012, 10:226 (19 November 2012)

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Impact of passing mesenchymal stem cells through smaller bore size needles for subsequent use in patients for clinical or cosmetic indications

Murali Mamidi, Gurbind Singh, Juani Husin, Kavitha Nathan, Gopinath Sasidharan, Zubaidah Zakaria, Ramesh Bhonde, Anish Majumdar, Anjan Das Journal of Translational Medicine 2012, 10:229 (21 November 2012)

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After insufficient radiofrequency ablation, tumor-associated endothelial cells exhibit enhanced angiogenesis and promote invasiveness of residual hepatocellular carcinoma

Jian Kong, Lingqun Kong, Jinge Kong, Shan Ke, Jun Gao, Xuemei Ding, Lemin Zheng, Huichuan Sun, Wenbing Sun Journal of Translational Medicine 2012, 10:230 (21 November 2012)

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Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome

Rosa Calemma, Alessandro Ottaiano, Anna Trotta, Guglielmo Nasti, Carmela Romano, Maria Napolitano, Domenico Galati, Pasquale Borrelli, Serena Zanotta, Antonino Cassata, Giuseppe Castello, Vincenzo Iaffaioli, Stefania Scala Journal of Translational Medicine 2012, 10:232 (21 November 2012)

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Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model

Raphael Thuillier, Ricardo Codas, Etienne Marchand, Hubert Lathelize, Olivier Page, Alexandre Valagier, Lionel Badet, Thierry Hauet Journal of Translational Medicine 2012, 10:233 (21 November 2012)

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Prothrombotic gene variants as risk factors of acute myocardial infarction in young women

Rossella Tomaiuolo, Chiara Bellia, Antonietta Caruso, Rosanna Di Fiore, Sandro Quaranta, Davide Noto, Angelo B Cefalù, Pierpaolo Di Micco, Federica Zarrilli, Giuseppe Castaldo, Maurizio R Averna, Marcello Ciaccio Journal of Translational Medicine 2012, 10:235 (21 November 2012)

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Safety profile and pharmacokinetic analyses of the anti-CTLA4 antibody tremelimumab administered as a one hour infusion

Antoni Ribas, Jason A Chesney, Michael S Gordon, Amy P Abernethy, Theodore F Logan, David H Lawson, Bartosz Chmielowksi, John A Glaspy, Karl Lewis, Bo Huang, Erjian Wang, Poe-Hirr Hsyu, Jesus Gomez-Navarro, Diana Gerhardt, Margaret A Marshall, Rene Gonzalez Journal of Translational Medicine 2012, 10:236 (21 November 2012)

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High-Intensity Interval Resistance Training (HIRT) influences resting energy expenditure and respiratory ratio in non-dieting individuals

Antonio Paoli, Tatiana Moro, Giuseppe Marcolin, Marco Neri, Antonino Bianco, Antonio Palma, Keith Grimaldi Journal of Translational Medicine 2012, 10:237 (24 November 2012)

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Myosin heavy chain 2A and α-Actin expression in human and murine skeletal muscles at feeding; particularly amino acids

Britt-Marie Iresjö, Kent Lundholm Journal of Translational Medicine 2012, 10:238 (28 November 2012)

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The association of blood angioregulatory microRNA levels with circulating endothelial cells and angiogenic proteins in patients receiving dacarbazine and interferon

Pierre L Triozzi, Susan Achberger, Wayne Aldrich, Arun D Singh, Ronald Grane, Ernest C Borden Journal of Translational Medicine 2012, 10:241 (5 December 2012)

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Overexpression of the secretory small GTPase Rab27B in human breast cancer correlates closely with lymph node metastasis and predicts poor prognosis

Jia-Xing Zhang, Xiao-Xia Huang, Man-Bo Cai, Zhu-Ting Tong, Jie-Wei Chen, Dong Qian, Yi-Ji Liao, Hai-Xia Deng, Ding-Zhun Liao, Ma-Yan Huang, Yi-Xin Zeng, Dan Xie, Shi-Juan Mai Journal of Translational Medicine 2012, 10:242 (5 December 2012)

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Pre-conditioned mesenchymal stem cells ameliorate renal ischemic injury in rats by augmented survival and engraftment

Muhammad Masoud, Sanam Anwar, Muhammad Afzal, Azra Mehmood, Shaheen N Khan, Sheikh Riazuddin Journal of Translational Medicine 2012, 10:243 (5 December 2012)

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Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in Rat sepsis syndrome induced by cecal puncture and ligation

Chia-Lo Chang, Steve Leu, Hsin-Ching Sung, Yen-Yi Zhen, Chung-Lung Cho, Angela Chen, Tzu-Hsien Tsai, Sheng-Ying Chung, Han-Tan Chai, Cheuk-Kwan Sun, Chia-Hung Yen, Hon-Kan Yip Journal of Translational Medicine 2012, 10:244 (7 December 2012)

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Research   Open Access

Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis

Zhi-Yuan Chen, Ming Shi, Li-Xia Peng, Wei Wei, Xin-Jian Li, Zhi-Xing Guo, Shu-Hong Li, Chong Zhong, Chao-Nan Qian, Rong-Ping Guo Journal of Translational Medicine 2012, 10:245 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104)

Thomas F Gajewski, April KS Salama, Donna Niedzwiecki, Jeffrey Johnson, Gerald Linette, Cynthia Bucher, Michelle A Blaskovich, Said M Sebti, Frank Haluska, the Cancer and Leukemia Group B Journal of Translational Medicine 2012, 10:246 (10 December 2012)

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Research   Open Access

Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma

Giuseppina Bonanno, Andrea Mariotti, Annabella Procoli, Valentina Folgiero, Daniela Natale, Luca De Rosa, Ignazio Majolino, Linda Novarese, Alberto Rocci, Manuela Gambella, Marilena Ciciarello, Giovanni Scambia, Antonio Palumbo, Franco Locatelli, Raimondo De Cristofaro, Sergio Rutella Journal of Translational Medicine 2012, 10:247 (11 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

JC virus detection and JC virus-specific immunity in natalizumab-treated Multiple Sclerosis patients

Roberta Mancuso, Marina Saresella, Ambra Hernis, Ivana Marventano, Cristian Ricci, Simone Agostini, Marco Rovaris, Domenico Caputo, Mario Clerici Journal of Translational Medicine 2012, 10:248 (11 December 2012)

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Research   Open Access

Nimotuzumab promotes radiosensitivity of EGFR-overexpression esophageal squamous cell carcinoma cells by upregulating IGFBP-3

Lei Zhao, Li-Ru He, Mian Xi, Mu-Yan Cai, Jing-Xian Shen, Qiao-Qiao Li, Yi-Ji Liao, Dong Qian, Zi-Zhen Feng, Yi-Xin Zeng, Dan Xie, Meng-Zhong Liu Journal of Translational Medicine 2012, 10:249 (11 December 2012)

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Research   Open Access Highly Accessed

MGMT promoter methylation status and MGMT and CD133 immunohistochemical expression as prognostic markers in glioblastoma patients treated with temozolomide plus radiotherapy

Consolación Melguizo, Jose Prados, Beatriz González, Raul Ortiz, Angel Concha, Pablo Alvarez, Roberto Madeddu, Gloria Perazzoli, Jaime Oliver, Rodrigo López, Fernando Rodríguez-Serrano, Antonia Aránega Journal of Translational Medicine 2012, 10:250 (17 December 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic lupus erythematosus

Vincent Biajoux, Alexandre Bignon, Christelle Freitas, Valérie Martinez, Marcus Thelen, Guadalupe Lima, Juan Jakez-Ocampo, Dominique Emilie, Luis Llorente, Karl Balabanian Journal of Translational Medicine 2012, 10:251 (18 December 2012)

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Research   Open Access

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

Simona Caporali, Lauretta Levati, Grazia Graziani, Alessia Muzi, Maria Grazia Atzori, Enzo Bonmassar, Giuseppe Palmieri, Paolo A Ascierto, Stefania D’Atri Journal of Translational Medicine 2012, 10:252 (21 December 2012)

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Research   Open Access

Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study

Roberto Flores, Jianxin Shi, Barbara Fuhrman, Xia Xu, Timothy D Veenstra, Mitchell H Gail, Pawel Gajer, Jacques Ravel, James J Goedert Journal of Translational Medicine 2012, 10:253 (21 December 2012)

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Research   Open Access

Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo

Chung-Wei Fan, Chun-Yu Chen, Kuei-Tien Chen, Chia-Rui Shen, Yung-Bin Kuo, Ya-Shan Chen, Yeh-Pin Chou, Wei-Shan Wei, Err-Cheng Chan Journal of Translational Medicine 2012, 10:254 (24 December 2012)

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Research   Open Access

The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway

Zheng-lin Chen, Ping-qing Gu, Kangsheng Liu, Ya-juan Su, Ling-juan Gao Journal of Translational Medicine 2012, 10:255 (26 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research   Open Access

Adenovirus-mediated delivery of interferon-γ gene inhibits the growth of nasopharyngeal carcinoma

Ran-yi Liu, Ying-hui Zhu, Ling Zhou, Peng Zhao, Hong-li Li, Lan-cai Zhu, Hong-yu Han, Huan-xin Lin, Liang Kang, Jiang-xue Wu, Wenlin Huang Journal of Translational Medicine 2012, 10:256 (28 December 2012)

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