Molecular signatures induced by interleukin-2 on peripheral blood mononuclear cells and T cell subsets

doi:10.1186/1479-5876-4-26

Journal of Translational Medicine

Volume 4

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Jin P
Wang E
Provenzano M
Deola S
Selleri S
Ren J
Voiculescu S
Stroncek D
Panelli MC
Marincola FM

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Wang E
Provenzano M
Deola S
Selleri S
Ren J
Voiculescu S
Stroncek D
Panelli MC
Marincola FM
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Molecular signatures induced by interleukin-2 on peripheral blood mononuclear cells and T cell subsets

Ping Jin¹^* , Ena Wang¹^* , Maurizio Provenzano² , Sara Deola¹ , Silvia Selleri¹ , Jiaqiang Ren¹ , Sonia Voiculescu¹ , David Stroncek¹ , Monica C Panelli¹ and Francesco M Marincola¹

¹Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, 20892, USA

²Immune Oncology Section, Department of Surgery, University Hospital ZLF, Hebelstrasse 20, 4031, Basel, Switzerland

author email corresponding author email* Contributed equally

Journal of Translational Medicine 2006, 4:26doi:10.1186/1479-5876-4-26


Published:	28 June 2006

Additional files

Additional file 1:

Genes differentially expressed between non-treated and rIL-2 treated PBMC from 47 donors; 1,690 genes were identified to be significantly differentially expressed at a paired t test cut-off p₂-value < 0.005 (see Table 1).

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Additional file 2:

Sequence information about the IL-2Rβ chain in the 47 donors.

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Additional file 3:

Transcriptional alterations induced in CD4 and CD8 T cells by rIL-2 in the presence or absence of PBMC at a paired t test cut-off p₂-value < 0.005.

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