|
The level of agreement between the t test, SAM and PLS-DA for selecting differentially expressed genes from the same data set. |
|||||
| Type of array |
N.o. of differently expressed genes between dissected and control aorta |
Agreement between all three methods |
|||
|
|
|||||
| t-test P < 0.01 |
SAM |
PLS-DA |
|||
|
|
|||||
| Human Broad I cDNA array |
43 |
37 |
35 |
29 |
|
| Agreement with t-test |
- |
29 (67%) |
35 (81%) |
- |
|
| Cardiovascular cDNA array |
31 |
36 |
34 |
22 |
|
| Agreement with t-test |
- |
27 (87%) |
26 (84%) |
- |
|
| Affymetrix HG-133A |
242 |
195 |
79 |
79 |
|
| Agreement with t-test |
- |
195 (81%) |
79 (33%) |
- |
|
Weis-Müller et al. Journal of Translational Medicine 2006 4:29 doi:10.1186/1479-5876-4-29 |
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