Figure 1.

Proposed model of how IL-1 indirectly alters tumor growth and metastatic potential in vivo. In the tumor microenvironment IL-1 has local effects on host infiltrating cells that result in production of proangiogenic and prometastatic mediators.

Lewis et al. Journal of Translational Medicine 2006 4:48   doi:10.1186/1479-5876-4-48
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