Inhibition of lung metastases in IL-1ra over-expressing melanoma xenografts. There was marked inhibition of lung metastases from the SMEL/IL-1ra cells compared with the null-transduced and wild-type controls. Cells were injected via tail vein, and the lungs were harvested 28 days later.
Lewis et al. Journal of Translational Medicine 2006 4:48 doi:10.1186/1479-5876-4-48