Figure 2.

Ex-vivo detection of modified TRP2:180–188-specific IFN-γ producing splenocytes (spot forming cells, SFC) in mice 8 days following a single immunization against TRP2:180–188 in VM. Mice immunized against TRP2:180–188 in VM with CpG adjuvant produced the largest number of cytotoxic T cells. Omission of CpG from the vaccine produced approximately one-half as many SFC. TRP2:180–188 alone and an irrelevant peptide with CpG in VM produced background numbers of SFC.