|
Characteristics associated with changes in CD39 function |
||
| Characteristics |
Activity (pmol/min/50 K cells) |
|
|
|
||
| Stage |
0–2 |
88.2* |
| 3–4 |
44.7 |
|
| History of chemotherapy? |
Yes |
55.8 |
| No |
83** |
|
| Age |
< = 70 y/o |
46.5* |
| > 70 y/o |
92 |
|
| Hemoglobin |
< 13 g/dl |
57.9† |
| > = 13 g/dl |
89.4 |
|
|
Statistically significant differences in CD39 activity. Stage, age, and hemoglobin levels were associated with statistically significant differences in the enzymatic activity of CD39 in patients with CLL. A history of chemotherapy was associated with a marginally significant trend towards decreased CD39 activity in CLL. Leukocyte and platelet count, gender, and length of time since diagnosis were not associated with differences in CD39 activity. *p = 0.002 **p = 0.08 †p = 0.03 | ||
Pulte et al. Journal of Translational Medicine 2007 5:23 doi:10.1186/1479-5876-5-23 |
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