|
aPTT coagulation time of normal plasma and Leiden plasma (100 μL) with and without incubation for 5 minutes with peptide 1–16 or NaCl as control. |
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| Plasmas incubated with peptide 1–16 |
aPTT coagulation time (sec.) |
Plasmas incubated with NaCl |
aPTT coagulation time (sec.) |
p |
|
|
||||
| Normal plasma incubated at T0 with peptide 1–16 |
40 ± 5 |
Normal plasma incubated at T0 with NaCl |
38 ± 3 |
0,16 |
| Leiden plasma incubated at T0 with peptide 1–16 |
41 ± 4 |
Leiden plasma incubated at T0 with NaCl |
40 ± 4 |
0,59 |
| Normal plasma incubated with peptide 1–16 at T1 |
90 ± 6 |
Normal plasma incubated at T1 with NaCl |
37 ± 4 |
0,000 |
| Leiden plasma incubated at T1 with peptide 1–16 |
120 ± 9 |
Leiden plasma incubated at T1 with NaCl |
38 ± 3 |
0,000 |
|
aPTT: activated partial thromboplastin time sec.: seconds T0: time of incubation T1: 5 minutes after the incubation NaCl: sodium clorure | ||||
Di Micco et al. Journal of Translational Medicine 2007 5:69 doi:10.1186/1479-5876-5-69 |
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