Table 2

Increases in CD4+ CD25+ T Cells after IL-2 Therapy; Percentages of CD25+ CD4+ T Cells

scIL-2 dose
Baseline
After 3 Cycles
Change

7.5 MIU
1.0 ± 0.7
10.7 ± 6.7
9.7 ± 6.7
1.5 MIU
0.9 ± 0.6
3.9 ± 2.5
2.9 ± 2.6
Control
1.5 ± 0.9
2.9 ± 1.4
1.5 ± 1.1

Percentages of CD25+ CD4+ T cells at baseline and after 3 cycles of scIL-2 therapy (week 24). The high dose IL-2 produced the greatest increase in CD25 percentages after scIL-2 administration. The high group had 4, the low group has 5 and none had 3.

Lewis et al. Journal of Translational Medicine 2007 5:9   doi:10.1186/1479-5876-5-9