Table 3

Increases in CD4+ T Cells after IL-2 Therapy; Numbers of CD25+ CD4+ T Cells

scIL-2 dose
Baseline
After 3 Cycles
Change

7.5 MIU
16.6 ± 13.0
315.4 ± 196.7
299 ± 199
1.5 MIU
12.8 ± 13.6
110.6 ± 103.9
98 ± 111
Control
22.3 ± 15.6
52.3 ± 15.3
30 ± 23

Numbers of CD25+ CD4+ T cells at baseline and after 3 cycles of scIL-2 therapy (week 24). The high dose IL-2 produced the greatest increase in CD25 numbers after scIL-2 administration. The high group had 4, the low group has 5 and none had 3.

Lewis et al. Journal of Translational Medicine 2007 5:9   doi:10.1186/1479-5876-5-9