Table 4

CD8 Annexin V Levels at Baseline and 6 Years.

% Annexin V levels (mean ± SD)
Baseline (mean ± SD)
6 Years (mean ± SD)



CD4 (cells/mm3)
CD8 (cells/mm3)
CD4:CD8 Ratio
CD4 (cells/mm3)
CD8 (cells/mm3)
CD4:CD8 Ratio

Low 2.2 ± 2.1
625 ± 221
967 ± 386
0.76 ± 0.4
1209 ± 164
915 ± 308
1.55 ± 0.9
High 17.0 ± 6.0
527 ± 132
1234 ± 660
0.56 ± 0.36
754 ± 320
1172 ± 456
0.76 ± 0.4
p-value
p = 0.331
p = 0.374
p = 0.327
p = 0.001
p = 0.240
p = 0.038

CD4 values, CD8 values, and CD4:CD8 ratios were recorded at baseline and 6 years for the low and high apoptosis groups. At baseline, a parametric t test showed no significance between low and high CD8 apoptosis levels for CD4, CD8 or CD4:CD8 ratios. However, after 6 years, a significant difference was observed between the high and low annexin groups with respect to CD4 values and CD4:CD8 ratios with p values of ≥ 0.001 and ≥ 0.037. CD8 was not significantly different at any time point.

Lewis et al. Journal of Translational Medicine 2007 5:9   doi:10.1186/1479-5876-5-9