|
CD8 Annexin V Levels at Baseline and 6 Years. |
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| % Annexin V levels (mean ± SD) |
CD4 (cells/mm3) |
CD8(cells/mm3) |
CD4:CD8 Ratio |
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|
|
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| Baseline |
6 YR |
P-value |
Baseline |
6 YR |
P-value |
Baseline |
6 YR |
P-value |
|
|
|
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| Low 2.2 ± 2.1 |
625 ± 221 |
1209 ± 164 |
0.001 |
967 ± 386 |
915 ± 308 |
0.766 |
0.76 ± 0.4 |
1.55 ± 0.9 |
0.038 |
| High 17.0 ± 6.0 |
527 ± 132 |
754 ± 320 |
0.098 |
1234 ± 660 |
1172 ± 456 |
0.728 |
0.56 ± 0.36 |
0.7 ± 0.34 |
0.215 |
|
A repeated measures ANOVA showed a significant difference in the low annexin group for CD4 values from baseline to year 6 with a p value of p ≥ 0.001. The high annexin group CD4 values were not significant from baseline to year 6 with a p value of ≥ 0.098. CD8 values in both the low and high apoptosis groups were not significant for the baseline or 6 year analysis. The CD4:CD8 ratio for the low apoptosis group was significant with a p value of ≥ 0.038, but the ratio for the high apoptosis group was not significant (p ≥ 0.215) after 6 years. | |||||||||
Lewis et al. Journal of Translational Medicine 2007 5:9 doi:10.1186/1479-5876-5-9 |
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