Table 1

Promoter methylation status of MAL in cell lines of various tissues.

Cell line
Tissue
Promoter methylation status
Methylation frequency

BT-20
Breast
M
57%
BT-474
Breast
U/M

Hs 578T
Breast
U

SK-BR-3
Breast
U

T-47D
Breast
U/M

ZR-75-1
Breast
U

ZR-75-38
Breast
M


Co115
Colon
M
95%
HCT15
Colon
M

HCT116
Colon
M

LoVo
Colon
M

LS174T
Colon
M

RKO
Colon
M

SW48
Colon
M

TC7
Colon
M

TC71
Colon
M

ALA
Colon
M

Colo320
Colon
M

EB
Colon
M

FRI
Colon
U/M

HT29
Colon
M

IS1
Colon
M

IS2
Colon
M

IS3
Colon
M

LS1034
Colon
M

SW480
Colon
M

V9P
Colon
U


ACHN
Kidney
U
50%
Caki-1
Kidney
U

Caki-2
Kidney
M

786-O
Kidney
U/M


ES-2
Ovary
U/M
50%
OV-90
Ovary
U/M

Ovcar-3
Ovary
U

SK-OV-3
Ovary
U


AsPC-1
Pancreas
M
67%
BxPC-3
Pancreas
U

CFPAC-1
Pancreas
U

HPAF-II
Pancreas
M

PaCa-2
Pancreas
M

Panc-1
Pancreas
U/M


LNCaP
Prostate
U
0%

AN3 CA
Uterus
U/M
75%
HEC-1-A
Uterus
M

KLE
Uterus
U

RL95-2
Uterus
M


The promoter methylation status of the individual cell lines was assessed by methylation-specific polymerase chain reaction (MSP). The methylation frequency reflects the number of methylated (M and U/M) samples from each tissue. Abbreviations: U, unmethylated; M, methylated.

Lind et al. Journal of Translational Medicine 2008 6:13   doi:10.1186/1479-5876-6-13