Table 2

Top 70 up-regulated genes

No.
Gene symbol
False discovery rate
Fold difference
Description

1
SCAM-1
< 1e-07
22.68
vinexin beta (SH3-containing adaptor molecule-1)
2
SNTB1
< 1e-07
22.04
syntrophin, beta 1 (dystrophin-associated protein A1, 59 kDa, basic component 1)
3
DMWD
< 1e-07
21.75
dystrophia myotonica-containing WD repeat motif
4
NPFF
< 1e-07
20.72
neuropeptide FF-amide peptide precursor
5
FXYD3
< 1e-07
6.97
FXYD domain containing ion transport regulator 3
6
ATP6V0B
< 1e-07
5.77
ATPase, H+ transporting, lysosomal 21 kDa, V0 subunit c"
7
PPIB
< 1e-07
4.64
peptidylprolyl isomerase B (cyclophilin B)
8
HIST1H4C
< 1e-07
3.81
histone 1, H4c
9
PHB
9.40e-06
7.07
prohibitin
10
NME1
9.40e-06
5.00
non-metastatic cells 1, protein (NM23A) expressed in
11
NDUFA9
9.40e-06
3.34
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39 kDa
12
BUB1B
1.20e-05
2.77
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
13
GRK5
1.34e-05
21.03
G protein-coupled receptor kinase 5
14
TPI1
1.34e-05
10.82
triosephosphate isomerase 1
15
CYC1 *
1.34e-05
10.36
cytochrome c-1
16
GPC5
1.55e-05
19.28
glypican 5
17
BYSL
1.67e-05
41.59
bystin-like
18
COX5B
1.67e-05
12.52
cytochrome c oxidase subunit Vb
19
KATNB1
1.84e-05
18.37
katanin p80 (WD repeat containing) subunit B 1
20
PRKAB2
2.03e-05
14.24
protein kinase, AMP-activated, beta 2 non-catalytic subunit
21
PSMB3
2.03e-05
7.43
proteasome (prosome, macropain) subunit, beta type, 3
22
PET112L
2.16e-05
21.46
PET112-like (yeast)
23
PSMD8
2.16e-05
4.88
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
24
CSF1
2.25e-05
20.35
colony stimulating factor 1 (macrophage)
25
SFTPA2
2.25e-05
17.66
surfactant, pulmonary-associated protein A2
26
PTCD1
2.25e-05
7.36
pentatricopeptide repeat domain 1
27
AARS
2.25e-05
6.65
alanyl-tRNA synthetase
28
GUK1
2.58e-05
5.61
guanylate kinase 1
29
RPS5
2.58e-05
4.66
ribosomal protein S5
30
MTL5
3.3e-05
14.60
metallothionein-like 5, testis-specific (tesmin)
31
MIF *
3.8e-05
10.72
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
32
POLR2H
3.94e-05
4.68
polymerase (RNA) II (DNA directed) polypeptide H
33
IFITM2
4.38e-05
4.17
interferon induced transmembrane protein 2 (1–8D)
34
MUTYH
4.41e-05
19.61
mutY homolog (E. coli)
35
ITPKA
4.41e-05
15.19
inositol 1,4,5-trisphosphate 3-kinase A
36
FDPS
5.36e-05
3.45
farnesyl diphosphate synthase
37
HIST1H2BG
6.08e-05
10.23
histone 1, H2bg
38
INPP5D
6.15e-05
17.02
inositol polyphosphate-5-phosphatase, 145 kDa
39
IDH3G
6.47e-05
47.05
isocitrate dehydrogenase 3 (NAD+) gamma
40
ERF
6.49e-05
15.57
Ets2 repressor factor
41
PTPRJ
6.54e-05
13.86
protein tyrosine phosphatase, receptor type, J
42
ATP5G1
7.90e-05
4.82
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c, isoform 1
43
CDC45L
8.49e-05
22.94
CDC45 cell division cycle 45-like (S. cerevisiae)
44
ENO1
9.67e-05
4.75
enolase 1, (alpha)
45
IDH3B
0.0001064
3.81
isocitrate dehydrogenase 3 (NAD+) beta
46
ST3GAL4
0.0001140
28.99
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
47
DDR2
0.0001152
15.87
discoidin domain receptor family, member 2
48
IFI30
0.0001188
3.88
interferon, gamma-inducible protein 30
49
EIF4G1
0.0001282
3.31
eukaryotic translation initiation factor 4 gamma, 1
50
CXorf27
0.0001372
11.62
chromosome X open reading frame 27
51
EPB41
0.0001423
4.05
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
52
RPS15
0.0001427
6.91
ribosomal protein S15
53
ABCA3
0.0001432
30.18
ATP-binding cassette, sub-family A (ABC1), member 3
54
CGA
0.0001508
12.31
glycoprotein hormones, alpha polypeptide
55
SLC37A4
0.0001527
23.08
solute carrier family 37 (glycerol-6-phosphate transporter), member 4
56
NDUFB8
0.0001527
3.56
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19 kDa
57
CSPG4
0.0001583
60.14
chondroitin sulfate proteoglycan 4 (melanoma-associated)
58
MTHFD1
0.0001583
21.57
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1,
59
CYP3A5
0.0001586
17.90
cytochrome P450, family 3, subfamily A, polypeptide 5
60
FKBP4
0.0001611
6.51
FK506 binding protein 4, 59 kDa
61
SCO2
0.0001760
14.31
SCO cytochrome oxidase deficient homolog 2 (yeast)
62
DPM2
0.0001846
12.99
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
63
NRGN
0.0001945
16.26
neurogranin (protein kinase C substrate, RC3)
64
TUBA2
0.0001988
8.87
tubulin, alpha 2
65
GAPD
0.0001990
4.99
glyceraldehyde-3-phosphate dehydrogenase
66
CDK4
0.0002205
6.73
cyclin-dependent kinase 4
67
BIRC5
0.0002380
6.62
baculoviral IAP repeat-containing 5 (survivin)
68
LAMB3 *
0.0002380
5.33
laminin, beta 3
69
SSR4
0.0002380
3.81
signal sequence receptor, delta (translocon-associated protein delta)
70
PIK4CA
0.0002398
12.01
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide

* Genes appeared in table 4

Fang et al. Journal of Translational Medicine 2008 6:32   doi:10.1186/1479-5876-6-32