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Genes differentially expressed between hematopoietic stem cells (HSCs) and peripheral blood leukocytes (PBLs) |
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| Expression Increased in HSCs |
Expression Increased in PBLs |
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| Gene Symbol |
Description |
Fold Change |
Gene Symbol |
Description |
Fold Change |
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| GATA2 |
GATA-binding protein 2 |
237.82 |
CARD14 |
Caspase recruitment domain protein 14 |
25.59 |
| MYCN |
N-myc |
97.75 |
LTBR |
Lymphotoxin-Beta receptor precursor = Tumor necrosis factor receptor 2 related protein = Tumor necrosis factor C receptor |
18.83 |
| CRHBP |
CRF-BP = corticotropin-releasing factor binding protein |
65.52 |
GPR65 |
TDAG8 = putative G protein-coupled receptor induced during activation-induced apoptosis of T cells = G protein-coupled receptor 65 |
18.33 |
| FHL1 |
Four and a half LIM domains 1 |
58.2 |
FCGR3A |
CD16 = Fcgamma receptor IIIa |
18.15 |
| ERG |
V-ets erythroblastosis virus E26 oncogene homolog (avian) |
43.57 |
ITGAM |
Integrin, alpha M (complement component 3 receptor 3 subunit) |
16.96 |
| NPR3 |
Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) |
42.04 |
SGSH |
N-sulfoglucosamine sulfohydrolase (sulfamidase) |
16.64 |
| SCHIP1 |
Schwannomin interacting protein 1 |
41.77 |
ITGB7 |
Integrin, beta 7 |
16.39 |
| MSRB3 |
Methionine sulfoxide reductase B3 |
35.29 |
GNLY |
Granulysin |
15.21 |
| MYB |
V-myb myeloblastosis viral oncogene homolog (avian) |
32.99 |
ALOX5AP |
Arachidonate 5-lipoxygenase-activating protein |
15.11 |
| DEPDC6 |
DEP domain containing 6 |
28.85 |
CD48 |
CD48 = BLAST-1 |
14.81 |
| EPDR1 |
Ependymin related protein 1 (zebrafish) |
27.88 |
IL10RA |
Interleukin 10 receptor, alpha |
13.71 |
| TRH |
Thyrotropin-releasing hormone |
26.63 |
CX3CR1 |
Chemokine (C-X3-C motif) receptor 1 |
13.64 |
| NGFRAP1 |
Nerve growth factor receptor (TNFRSF16) associated protein 1 |
25.86 |
COTL1 |
Coactosin-like 1 (Dictyostelium) |
13.4 |
| SERPING1 |
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) |
25.83 |
ADAM19 |
ADAM metallopeptidase domain 19 (meltrin beta) |
13.24 |
| MAP7 |
Microtubule-associated protein 7 |
25.11 |
IL2RB |
IL-2 receptor beta chain |
13 |
| SOCS2 |
Suppressor of cytokine signaling 2 |
24.44 |
ITK |
IL2-inducible T-cell kinase |
11.91 |
| TSC22D1 |
TSC22 domain family, member 1 |
24.12 |
KLRC4 |
Killer cell lectin-like receptor subfamily C, member 4 |
11.36 |
| H1F0 |
H1 histone family, member 0 |
22.71 |
CCL4 |
MIP-1 beta |
11.22 |
| RBPMS |
RNA binding protein with multiple splicing |
22.67 |
CTSH |
Cathepsin H |
11.18 |
| CTDSPL |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
22.64 |
EBI2 |
Epstein-Barr virus induced gene 2 (lymphocyte-specific G protein-coupled receptor) |
10.69 |
| CDCA7 |
Cell division cycle associated 7 |
22.49 |
GIMAP4 |
GTPase, IMAP family member 4 |
10.28 |
| CYTL1 |
Cytokine-like 1 |
20.9 |
POU2F2 |
POU domain, class 2, transcription factor 2 |
10.22 |
| FLT3 |
Fms-related tyrosine kinase 3 |
20.45 |
CXCR4 |
CXCR4 = CXC chemokine receptor 4 |
10.11 |
| PRKAR2B |
Protein kinase, cAMP-dependent, regulatory, type II, beta |
20.09 |
CYP4A11 |
Cytochrome P450, family 4, subfamily A, polypeptide 11 |
10.1 |
| TRIM58 |
Tripartite motif-containing 58 |
19.18 |
LGALS3 |
Lectin, galactoside-binding, soluble, 3 (galectin 3) |
9.61 |
| FSCN1 |
Fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) |
18.91 |
SNX27 |
Sorting nexin family member 27 |
9.44 |
| C1orf150 |
Chromosome 1 open reading frame 150 |
18.83 |
TRIM26 |
Tripartite motif-containing 26 |
9.23 |
| TRH |
Thyrotropin-releasing hormone |
17.56 |
SNX27 |
Sorting nexin family member 27 |
9.05 |
| KIT |
V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
17.27 |
CSPG2 |
Chondroitin sulfate proteoglycan 2 (versican) |
8.89 |
| WASF1 |
WAS protein family, member 1 |
16.75 |
IL32 |
Interleukin 32 |
8.76 |
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*The groups were compared using t-tests (p < 0.001). | |||||
Jin et al. Journal of Translational Medicine 2008 6:39 doi:10.1186/1479-5876-6-39 |
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