The expression of CD133 in colon cancer patients with stage IIIB (10 × 20~10 × 100). The expression of CD133 was examined with immunohistochemical assay. (A): <5% CD133+ cells in the cancer nest; (B): ≥5% CD133+ cells in the cancer nest; (C) and (D): the staining of CD133 on the luminal surface and the basal surface of cancer cells; (E): the staining of CD133 on budding cancer nest; (F): the staining of CD133 on poor-differentiated cancer nests with ductal structures.
Li et al. Journal of Translational Medicine 2009 7:56 doi:10.1186/1479-5876-7-56