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Open Access Highly Accessed Review

Biomedical informatics and translational medicine

Indra Neil Sarkar

Author Affiliations

Center for Clinical and Translational Science, Department of Microbiology and Molecular Genetics, & Department of Computer Science, University of Vermont, College of Medicine, 89 Beaumont Ave, Given Courtyard N309, Burlington, VT 05405 USA

Journal of Translational Medicine 2010, 8:22  doi:10.1186/1479-5876-8-22

Published: 26 February 2010

Abstract

Biomedical informatics involves a core set of methodologies that can provide a foundation for crossing the "translational barriers" associated with translational medicine. To this end, the fundamental aspects of biomedical informatics (e.g., bioinformatics, imaging informatics, clinical informatics, and public health informatics) may be essential in helping improve the ability to bring basic research findings to the bedside, evaluate the efficacy of interventions across communities, and enable the assessment of the eventual impact of translational medicine innovations on health policies. Here, a brief description is provided for a selection of key biomedical informatics topics (Decision Support, Natural Language Processing, Standards, Information Retrieval, and Electronic Health Records) and their relevance to translational medicine. Based on contributions and advancements in each of these topic areas, the article proposes that biomedical informatics practitioners ("biomedical informaticians") can be essential members of translational medicine teams.