Ratios of infarct area to total coronal sectional area using TTC staining. (A to E) Identification of gross infarct area (green circles) in animals with B) ischemic stroke (IS) (group 2), C) IS + cyclosporine (CsA) (group 3), D) IS + erythropoietin (EPO) (group 4) and E) IS + combined CsA & EPO (group 5), respectively. (F) Significantly lower ratio of infarct area to total coronal sectional area in group 5 than in group 2, 3, and 4, and notably lower in group 3 and 4 than in group 2 (n = 6 for each group). * vs. other groups, p < 0.0001 (using ANOVA). Symbols (*, †, ‡) indicate significance (at 0.05 level) (by Scheffe multiple-comparison post hoc test).
Yuen et al. Journal of Translational Medicine 2011 9:141 doi:10.1186/1479-5876-9-141