Distribution of glial fibrillary acid protein (GFAP) and aquaporin-4 (AQP-4) in brain infarct area. A) to E) Immunofluorescent staining (400 x) of glial fibrillary acid protein (GFAP) (white arrows) and aquaporin-4 (AQP-4) (yellow arrows) in brain infarct area (n = 6). Both numbers of GFAG and AQP-4 remarkably higher in group 2 than in other groups, notably higher in group 3 and 4 than in group 1 and 5, and significantly higher in group 5 than in group 1. F) and G) † vs. other groups, p < 0.0001 (ANOVA test). Symbols (*, †, ‡, §) in (F) and (G) indicate significance (at 0.05 level) (by Scheffe multiple-comparison post hoc test). Scale bars in right lower corner represent 20 μm.
Yuen et al. Journal of Translational Medicine 2011 9:141 doi:10.1186/1479-5876-9-141