The comparison of miRNA profile in ESCC cell lines (OE21 or TE10) and non-ESCC cell line (Het1A). MicroRNA (miR) microarray showed that miR-203, -429, -205, -200c, and -141 were significantly (more than 2-fold) overexpressed in the 2 esophageal squamous cell carcinoma (ESCC) cell lines, OE21 (while bars) and TE10 (black bars), compared to the non-malignant esophageal squamous cell line, Het1A cells (A). On the other hand, miR-153, -100, -125b, -10a, -99a, -376a, -379, -651, and -146b were significantly reduced in expression in both ESCC cell lines compared to Het-1A cells (B).
Matsushima et al. Journal of Translational Medicine 2011 9:30 doi:10.1186/1479-5876-9-30