Length-dependent activation. When the muscle was stretched from 85% of optimal length (near slack, virtually no passive tension, 37°C) to optimal length, active force development significantly increased in both NBD treated and vehicle treated groups. Repeated measures ANOVA indicated that impact of both factors, treatment and length, were significant (P < 0.05), but not the interaction, indicating unchanged length-dependent behavior after NBD treatment in dko mice. * indicates a difference of P < 0.05 between the two groups.
Delfín et al. Journal of Translational Medicine 2011 9:68 doi:10.1186/1479-5876-9-68