%PDF-1.6
%
1 0 obj
<>
endobj
2 0 obj
<>stream
2015-07-13T14:10:32+05:30
Springer
2015-07-13T18:03:23+02:00
2015-07-13T18:03:23+02:00
Acrobat Distiller 10.1.8 (Windows); modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (AGPL-version)
PARP inhibition; Olaparib (AZD2281); Allergen-induced eosinophilia; Adoptive transfer; Th2 cytokines; Allergen-specific IgE
application/pdf
doi:10.1186/s12967-015-0583-0
BioMed Central
Journal of Translational Medicine, doi:10.1186/s12967-015-0583-0
PARP inhibition; Olaparib (AZD2281); Allergen-induced eosinophilia; Adoptive transfer; Th2 cytokines; Allergen-specific IgE
PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function
Mohamed A Ghonim
Kusma Pyakurel
Salome V Ibba
Amir A Al-Khami
Jeffrey Wang
Paulo Rodriguez
Hamada F Rady
Ali H El-Bahrawy
Matthew R Lammi
Moselhy S Mansy
Kamel Al-Ghareeb
Alistair Ramsay
Augusto Ochoa
Amarjit S Naura
A Hamid Boulares
10.1186/s12967-015-0583-0
2010-04-23
true
springer.com
springerlink.com
"http://dx.doi.org/10.1186/s12967-015-0583-0
10.1186/s12967-015-0583-0
1479-5876
journal
Journal of Translational Medicine
Ghonim et al.
2010-04-23
true
10.1186/s12967-015-0583-0
noindex
springer.com
springerlink.com
uuid:0ac5c9e1-9405-4e8b-82cc-ff2c8dc2c234
uuid:b87147c0-8b70-4194-84d2-d8f372e6372b
default
1
converted
uuid:c524a81a-a644-4460-aaf0-fe168d0a876c
converted to PDF/A-2b
pdfToolbox
2015-07-13T14:11:27+05:30
converted
uuid:594f8b5b-b3fb-4afa-8b84-f501a22da50a
converted to PDF/A-2b
pdfToolbox
2015-07-13T14:12:10+05:30
2
B
http://ns.adobe.com/pdfx/1.3/
pdfx
PDF/X ID Schema
external
Mirrors crossmark:MajorVersionDate
CrossmarkMajorVersionDate
Text
external
Mirrors crossmark:CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
Mirrors crossmark:DOI
doi
Text
external
Mirrors crossmark:CrosMarkDomains
CrossMarkDomains
seq Text
internal
A name object indicating whether the document has been modified to include trapping information
robots
Text
internal
ID of PDF/X standard
GTS_PDFXVersion
Text
internal
Conformance level of PDF/X standard
GTS_PDFXConformance
Text
internal
Company creating the PDF
Company
Text
internal
Date when document was last modified
SourceModified
Text
http://crossref.org/crossmark/1.0/
crossmark
Crossmark Schema
internal
Usual same as prism:doi
DOI
Text
external
The date when a publication was publishe.
MajorVersionDate
Text
internal
CrossmarkDomainExclusive
CrossmarkDomainExclusive
Text
internal
CrossMarkDomains
CrossMarkDomains
seq Text
http://prismstandard.org/namespaces/basic/2.0/
prism
Prism Schema
external
This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary.
url
URI
external
The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL).
doi
Text
external
ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version.
issn
Text
internal
Volume number
volume
Text
internal
Issue number
number
Text
internal
Starting page
startingPage
Text
internal
Ending page
endingPage
Text
external
The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary.
aggregationType
Text
external
Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.”
publicationName
Text
external
Copyright
copyright
Text
http://ns.adobe.com/pdf/1.3/
pdf
Adobe PDF Schema
internal
A name object indicating whether the document has been modified to include trapping information
Trapped
Text
http://ns.adobe.com/xap/1.0/mm/
xmpMM
XMP Media Management Schema
internal
UUID based identifier for specific incarnation of a document
InstanceID
URI
internal
The common identifier for all versions and renditions of a document.
DocumentID
URI
internal
The common identifier for all versions and renditions of a document.
OriginalDocumentID
URI
http://www.aiim.org/pdfa/ns/id/
pdfaid
PDF/A ID Schema
internal
Part of PDF/A standard
part
Integer
internal
Amendment of PDF/A standard
amd
Text
internal
Conformance level of PDF/A standard
conformance
Text
endstream
endobj
3 0 obj
<>/XObject<>/ProcSet[/PDF/Text]/Font<>>>/Thumb 17 0 R/MediaBox[0.0 0.0 595.276 793.701]/Annots 18 0 R/Rotate 0>>
endobj
18 0 obj
[19 0 R 20 0 R 21 0 R 22 0 R 23 0 R 24 0 R 25 0 R 26 0 R 27 0 R 28 0 R 29 0 R 30 0 R 31 0 R 32 0 R 33 0 R 34 0 R 35 0 R 36 0 R 37 0 R]
endobj
19 0 obj
<>/Rect[143.095 681.286 148.014 669.119]/H/N/AP<>>>
endobj
20 0 obj
<>/Rect[119.321 645.286 124.241 633.119]/H/N/AP<>>>
endobj
21 0 obj
<>/Rect[237.964 585.286 242.883 573.119]/H/N/AP<>>>
endobj
22 0 obj
<>/Rect[269.354 525.286 274.274 513.119]/H/N/AP<>>>
endobj
23 0 obj
<>/Rect[280.203 525.286 285.122 513.119]/H/N/AP<>>>
endobj
24 0 obj
<>/Rect[215.166 513.286 220.085 501.119]/H/N/AP<>>>
endobj
25 0 obj
<>/Rect[226.014 513.286 235.854 501.119]/H/N/AP<>>>
endobj
26 0 obj
<>/Rect[231.723 441.286 241.562 429.119]/H/N/AP<>>>
endobj
27 0 obj
<>/Rect[152.057 369.286 161.896 357.119]/H/N/AP<>>>
endobj
28 0 obj
<>/Rect[167.825 369.286 177.665 357.119]/H/N/AP<>>>
endobj
29 0 obj
<>/Rect[249.885 333.286 254.805 321.119]/H/N/AP<>>>
endobj
30 0 obj
<>/Rect[234.753 273.286 244.592 261.119]/H/N/AP<>>>
endobj
31 0 obj
<>/Rect[275.283 237.286 285.122 225.119]/H/N/AP<>>>
endobj
32 0 obj
<>/Rect[59.8876 177.286 69.7268 165.119]/H/N/AP<>>>
endobj
33 0 obj
<>/Rect[162.03 129.286 171.869 117.119]/H/N/AP<>>>
endobj
34 0 obj
<>/Rect[440.513 393.808 445.432 381.641]/H/N/AP<>>>
endobj
35 0 obj
<>/Rect[409.923 285.808 414.842 269.954]/H/N/AP<>>>
endobj
36 0 obj
<>/Rect[420.487 285.808 430.326 269.954]/H/N/AP<>>>
endobj
37 0 obj
<>/Rect[435.97 285.808 445.809 269.954]/H/N/AP<>>>
endobj
5 0 obj
<>stream
x\[wȑ~OH6v?0w,kksPx![U}@NH}W_US:g}Oߜ)*Y%dVq^HQIi)
Z}>I4N$g]/jIӤQ^1`20~UU`
oMYs!$u(dI57Wg-IR,ޝzś`8{B8Jcw̋:(<˼Jp̂uXunր4I$8:+w*LuwalL"$x۰ZnudUB56ͣ@bކ<"X:h~UP_I| 6F-Ԫ}LJvTETY)e-G{
fٱUa*Xڙ;' g̮ @3S[A8Anq.V=bAJ`Xd$z-4]ߪ].۞jy&v㇛Kb^!X*=XO_)YH=zA3jN~^OITXg@MX7˅xM W[Z[FmFA7bދߊ Np2d?Г:tvbNf8uy:^R?Vs]>q<Qc鐄ުz_kHc}lY82rd1n]xd":$qڨ9ZvQ5h^ѱ/|pNlf)u[.wؚ5^W9;hWp6ϻ7ɂ0w(V"8YKXUL((QU=JyIGIgq!Q! '5K9:\UI-Z?W*ɕs$%oOyzdہ[edI*ÆX-mF"DZͲsWnSEEϢ'[Ÿ=MQ}GuPǍUN]Ny]Gyfܣw-GqYtZ}Q fƤőݣ6Mn Puq}#&
rAP&](} 2ɍ*PP:@
ʪ[c VR]@H5u^}Y`e |a]ZP@tZhC(`FH{/Hdad"!?bp
)ײ'T4lҤ귽`?zϡ>isJ(~v(88;Jd\+9@ $F:.)X;Cgc, {~W$gˈfqjqsŬ3XW kYeIj"AYd.#]{ֻΎuQznϸ6O:_e7?]h^$ϡ}CI$eϷ~SiBj* 4NFhlju<`Dn1bz qP'+ʢOʞupjNn3x9d֧z!7jU5N0>aǂJ? dLAt_sFa/+c^'