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1.

1101
Accesses

Research   Open Access Highly Accessed

Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology

Elizabeth Ann Stringer, Katharine Susanne Baker, Ian R Carroll, Jose G Montoya, Lily Chu, Holden T Maecker, Jarred W Younger Journal of Translational Medicine 2013, 11:93 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

2.

1022
Accesses

Review   Open Access Highly Accessed

Exogenous endothelial cells as accelerators of hematopoietic reconstitution

J Mizer, Thomas E Ichim, Doru T Alexandrescu, Constantin A Dasanu, Famela Ramos, Andrew Turner, Erik J Woods, Vladimir Bogin, Michael P Murphy, David Koos, Amit N Patel Journal of Translational Medicine 2012, 10:231 (21 November 2012)

Abstract | Full text | PDF | PubMed

3.

876
Accesses

Commentary   Open Access Highly Accessed

The role of BRAF V600 mutation in melanoma

Paolo A Ascierto, John M Kirkwood, Jean-Jacques Grob, Ester Simeone, Antonio M Grimaldi, Michele Maio, Giuseppe Palmieri, Alessandro Testori, Francesco M Marincola, Nicola Mozzillo Journal of Translational Medicine 2012, 10:85 (3 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

803
Accesses

Research   Open Access Highly Accessed

Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer

Hiroyuki Suzuki, Mitsuro Fukuhara, Takumi Yamaura, Satoshi Mutoh, Naoyuki Okabe, Hiroshi Yaginuma, Takeo Hasegawa, Atsushi Yonechi, Jun Osugi, Mika Hoshino, Takashi Kimura, Mitsunori Higuchi, Yutaka Shio, Kazuya Ise, Kazuyoshi Takeda, Mitsukazu Gotoh Journal of Translational Medicine 2013, 11:97 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

787
Accesses

Review   Open Access Highly Accessed

RNA interference: learning gene knock-down from cell physiology

Simone Mocellin, Maurizio Provenzano Journal of Translational Medicine 2004, 2:39 (22 November 2004)

Abstract | Full text | PDF | PubMed

6.

768
Accesses

Review   Open Access Highly Accessed

Stem Cell Therapy for Autism

Thomas E Ichim, Fabio Solano, Eduardo Glenn, Frank Morales, Leonard Smith, George Zabrecky, Neil H Riordan Journal of Translational Medicine 2007, 5:30 (27 June 2007)

Abstract | Full text | PDF | PubMed

7.

761
Accesses

Research   Open Access Highly Accessed

Screening NK-, B- and T-cell phenotype and function in patients suffering from Chronic Fatigue Syndrome

Marta Curriu, Jorge Carrillo, Marta Massanella, Josepa Rigau, José Alegre, Jordi Puig, Ana M Garcia-Quintana, Jesus Castro-Marrero, Eugènia Negredo, Bonaventura Clotet, Cecilia Cabrera, Julià Blanco Journal of Translational Medicine 2013, 11:68 (20 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

740
Accesses

Research   Open Access Highly Accessed

Next-generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types

Inti Zlobec, Viktor H Koelzer, Heather Dawson, Aurel Perren, Alessandro Lugli Journal of Translational Medicine 2013, 11:104 (30 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

730
Accesses

Review   Open Access Highly Accessed

TGF-β – an excellent servant but a bad master

Lenka Kubiczkova, Lenka Sedlarikova, Roman Hajek, Sabina Sevcikova Journal of Translational Medicine 2012, 10:183 (3 September 2012)

Abstract | Full text | PDF | PubMed

10.

695
Accesses

Review   Open Access Highly Accessed

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

Shaheen E Lakhan, Annette Kirchgessner, Magdalena Hofer Journal of Translational Medicine 2009, 7:97 (17 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

687
Accesses

Research   Open Access

A systematic evaluation of miRNA:mRNA interactions involved in the migration and invasion of breast cancer cells

Daya Luo, James M Wilson, Nikki Harvel, Jimei Liu, Lirong Pei, Shuang Huang, LesleyAnn Hawthorn, Huidong Shi Journal of Translational Medicine 2013, 11:57 (5 March 2013)

Abstract | Full text | PDF | PubMed

12.

670
Accesses

Research   Open Access Highly Accessed

High-Intensity Interval Resistance Training (HIRT) influences resting energy expenditure and respiratory ratio in non-dieting individuals

Antonio Paoli, Tatiana Moro, Giuseppe Marcolin, Marco Neri, Antonino Bianco, Antonio Palma, Keith Grimaldi Journal of Translational Medicine 2012, 10:237 (24 November 2012)

Abstract | Full text | PDF | PubMed

13.

638
Accesses

Review   Open Access Highly Accessed

RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation

Louis J Sparvero, Denise Asafu-Adjei, Rui Kang, Daolin Tang, Neilay Amin, Jaehyun Im, Ronnye Rutledge, Brenda Lin, Andrew A Amoscato, Herbert J Zeh, Michael T Lotze Journal of Translational Medicine 2009, 7:17 (17 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

625
Accesses

Protocol   Open Access

Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites In Acute Myocardial Infarction (NIAMI)

Nishat Siddiqi, Margaret Bruce, Christopher J Neil, Baljit Jagpal, Graeme Maclennon, Seonaidh C Cotton, Sofia A Papadopoulo, Nicholas Bunce, Pit Lim, Konstantin Schwarz, Satnam Singh, David Hildick-Smith, John D Horowitz, Melanie Madhani, Nicholas Boon, Juan-Carlos Kaski, Dana Dawson, Michael P Frenneaux Journal of Translational Medicine 2013, 11:116 (6 May 2013)

Abstract | Provisional PDF | PubMed

15.

568
Accesses

Research   Open Access

BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas

Zhaoshi Bao, Chuanbao Zhang, Wei Yan, Yanwei Liu, Mingyang Li, Wei Zhang, Tao Jiang Journal of Translational Medicine 2013, 11:100 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

16.

570
Accesses

Review   Open Access Highly Accessed

Transfusion-transmitted infections

Florian Bihl, Damiano Castelli, Francesco Marincola, Roger Y Dodd, Christian Brander Journal of Translational Medicine 2007, 5:25 (6 June 2007)

Abstract | Full text | PDF | PubMed

17.

567
Accesses

Review   Open Access Highly Accessed

Bacteria and cancer: cause, coincidence or cure? A review

DL Mager Journal of Translational Medicine 2006, 4:14 (28 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

565
Accesses

Review   Open Access Highly Accessed

Identification and manipulation of tumor associated macrophages in human cancers

Moniek Heusinkveld, Sjoerd H van der Burg Journal of Translational Medicine 2011, 9:216 (16 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

562
Accesses

Research   Open Access Highly Accessed

Comparison of anti-CD3 and anti-CD28-coated beads with soluble anti-CD3 for expanding human T cells: Differing impact on CD8 T cell phenotype and responsiveness to restimulation

Yixin Li, Roger J Kurlander Journal of Translational Medicine 2010, 8:104 (26 October 2010)

Abstract | Full text | PDF | PubMed

20.

561
Accesses

Research   Open Access Highly Accessed

Effect of high-dose intravenous vitamin C on inflammation in cancer patients

Nina Mikirova, Joseph Casciari, Andrea Rogers, Paul Taylor Journal of Translational Medicine 2012, 10:189 (11 September 2012)

Abstract | Full text | PDF | PubMed

21.

557
Accesses

Research   Open Access

The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-alpha production

Stefania Laurent, Paola Queirolo, Silvia Boero, Sandra Salvi, Patrizia Piccioli, Simona Boccardo, Simona Minghelli, Anna Morabito, Vincenzo Fontana, Gabriella Pietra, Paolo Carrega, Nicoletta Ferrari, Francesca Tosetti, Lung-Ji Chang, Maria Cristina Mingari, Guido Ferlazzo, Alessandro Poggi, Maria Pia Pistillo Journal of Translational Medicine 2013, 11:108 (1 May 2013)

Abstract | Provisional PDF | PubMed

22.

555
Accesses

Research   Open Access

Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios

Arduino A Mangoni, Angelo Zinellu, Ciriaco Carru, John R Attia, Marc McEvoy Journal of Translational Medicine 2013, 11:99 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

23.

554
Accesses

Research   Open Access Highly Accessed

Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Ekua W Brenu, Mieke L van Driel, Don R Staines, Kevin J Ashton, Sandra B Ramos, James Keane, Nancy G Klimas, Sonya M Marshall-Gradisnik Journal of Translational Medicine 2011, 9:81 (28 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

551
Accesses

Commentary   Open Access Highly Accessed

Practical aspects in the management of hypokalemic periodic paralysis

Jacob O Levitt Journal of Translational Medicine 2008, 6:18 (21 April 2008)

Abstract | Full text | PDF | PubMed

25.

541
Accesses

Research   Open Access

Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer

Stephanie Weibel, Elisabeth Hofmann, Thomas Christian Basse-Luesebrink, Ulrike Donat, Carolin Seubert, Marion Adelfinger, Prisca Gnamlin, Christina Kober, Alexa Frentzen, Ivaylo Gentschev, Peter Michael Jakob, Aladar A Szalay Journal of Translational Medicine 2013, 11:106 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

26.

540
Accesses

Research   Open Access

SATB1 is overexpressed in metastatic prostate cancer and promotes prostate cancer cell growth and invasion

Lijun Mao, Chunhua Yang, Junqi Wang, Wang Li, Rumin Wen, Jiacun Chen, Junnian Zheng Journal of Translational Medicine 2013, 11:111 (4 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

27.

534
Accesses

Review   Open Access Highly Accessed

Endometrial regenerative cells for treatment of heart failure: a new stem cell enters the clinic

Leo Bockeria, Vladimir Bogin, Olga Bockeria, Tatyana Le, Bagrat Alekyan, Erik J Woods, Amalia A Brown, Thomas E Ichim, Amit N Patel Journal of Translational Medicine 2013, 11:56 (5 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Leo Bockeria and colleagues assess the effectiveness of aminimally invasive 30 minute delivery method of Endometrial Regenerative Cells in the treatment of heart failure

28.

535
Accesses

Review   Open Access Highly Accessed

Considerations in the development of circulating tumor cell technology for clinical use

David R Parkinson, Nicholas Dracopoli, Brenda Petty, Carolyn Compton, Massimo Cristofanilli, Albert Deisseroth, Daniel F Hayes, Gordon Kapke, Prasanna Kumar, Jerry SH Lee, Minetta C Liu, Robert McCormack, Stanislaw Mikulski, Larry Nagahara, Klaus Pantel, Sonia Pearson-White, Elizabeth A Punnoose, Lori T Roadcap, Andrew E Schade, Howard I Scher, Caroline C Sigman, Gary J Kelloff Journal of Translational Medicine 2012, 10:138 (2 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

533
Accesses

Research   Open Access

Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer

Xiaoxue Zhang, Rong Zhang, Yuanjie Zheng, Jianfei Shen, Dakai Xiao, Jin Li, Xiaoshun Shi, Liyan Huang, Hailing Tang, Jun Liu, Jianxing He, Haibo Zhang Journal of Translational Medicine 2013, 11:102 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

30.

517
Accesses

Research   Open Access Highly Accessed

Shipping blood to a central laboratory in multicenter clinical trials: effect of ambient temperature on specimen temperature, and effects of temperature on mononuclear cell yield, viability and immunologic function

Walter C Olson, Mark E Smolkin, Erin M Farris, Robyn J Fink, Andrea R Czarkowski, Jonathan H Fink, Kimberly A Chianese-Bullock, Craig L Slingluff Journal of Translational Medicine 2011, 9:26 (8 March 2011)

Abstract | Full text | PDF | PubMed

31.

494
Accesses

Review   Open Access Highly Accessed

Cytokine-induced killer cells promote antitumor immunity

Jingting Jiang, Changping Wu, Binfeng Lu Journal of Translational Medicine 2013, 11:83 (28 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

32.

488
Accesses

Review   Open Access Highly Accessed

Risk factors in the development of stem cell therapy

Carla A Herberts, Marcel SG Kwa, Harm PH Hermsen Journal of Translational Medicine 2011, 9:29 (22 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

486
Accesses

Research   Open Access Highly Accessed

Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice

Ghazanfar Ali Nasir, Sadia Mohsin, Mohsin Khan, Sulaiman Shams, Gibran Ali, Shaheen N Khan, Sheikh Riazuddin Journal of Translational Medicine 2013, 11:78 (26 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

34.

485
Accesses

Research   Open Access

Nuclear beta-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

Xi-Qing Li, Xing-Long Yang, Gong Zhang, Si-Pei Wu, Xu-Bing Deng, Sheng-Jun Xiao, Qiu-Zhen Liu, Kai-Tai Yao, Guang-Hui Xiao Journal of Translational Medicine 2013, 11:114 (6 May 2013)

Abstract | Provisional PDF | PubMed

35.

485
Accesses

Commentary   Open Access Highly Accessed

The site of origin of the 1918 influenza pandemic and its public health implications

John M Barry Journal of Translational Medicine 2004, 2:3 (20 January 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

36.

481
Accesses

Research   Open Access

The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation

Ling-juan Gao, Ping-qing Gu, Wei Zhao, Wen-yan Ding, Xue-qing Zhao, Shu-yu Guo, Tian-ying Zhong Journal of Translational Medicine 2013, 11:118 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

37.

478
Accesses

Research   Open Access Highly Accessed

Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance

Jennifer Pasquier, Bella S Guerrouahen, Hamda Al Thawadi, Pegah Ghiabi, Mahtab Maleki, Nadine Abu-Kaoud, Arthur Jacob, Massoud Mirshahi, Ludovic Galas, Shahin Rafii, Frank Le Foll, Arash Rafii Journal of Translational Medicine 2013, 11:94 (10 April 2013)

Abstract | Provisional PDF | PubMed

38.

475
Accesses

Review   Open Access Highly Accessed

Nerve growth factor: from the early discoveries to the potential clinical use

Luigi Aloe, Maria Rocco, Patrizia Bianchi, Luigi Manni Journal of Translational Medicine 2012, 10:239 (29 November 2012)

Abstract | Full text | PDF | PubMed

39.

474
Accesses

Review   Open Access Highly Accessed

Exosome removal as a therapeutic adjuvant in cancer

Annette M Marleau, Chien-Shing Chen, James A Joyce, Richard H Tullis Journal of Translational Medicine 2012, 10:134 (27 June 2012)

Abstract | Full text | PDF | PubMed

40.

467
Accesses

Review   Open Access Highly Accessed

Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis

Neil H Riordan, Thomas E Ichim, Wei-Ping Min, Hao Wang, Fabio Solano, Fabian Lara, Miguel Alfaro, Jorge Rodriguez, Robert J Harman, Amit N Patel, Michael P Murphy, Roland R Lee, Boris Minev Journal of Translational Medicine 2009, 7:29 (24 April 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Mesenchymal stem cells derived from the stromal vascular fraction of adipose tissue show promise in the treatment of multiple sclerosis and warrant further clinical evaluation.

41.

463
Accesses

Research   Open Access Highly Accessed

Body fluid derived exosomes as a novel template for clinical diagnostics

Sascha Keller, Johannes Ridinger, Anne-Kathleen Rupp, Johannes WG Janssen, Peter Altevogt Journal of Translational Medicine 2011, 9:86 (8 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

449
Accesses

Research   Open Access Highly Accessed

BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs

Michele Carbone, Laura Ferris, Francine Baumann, Andrea Napolitano, Christopher A Lum, Erin G Flores, Giovanni Gaudino, Amy Powers, Peter Bryant-Greenwood, Thomas Krausz, Elizabeth Hyjek, Rachael Tate, Joseph Friedberg, Tracey Weigel, Harvey I Pass, Haining Yang Journal of Translational Medicine 2012, 10:179 (30 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The presence of melanocytic tumors can provide physicians with a visual marker to identify individuals who may carry germline BAP1 mutations and so are at higher risk of developing melanoma and mesothelioma.

43.

449
Accesses

Research   Open Access

PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways

Lei Zhang, Shuang Wei, Jun-Ming Tang, Ling-Yun Guo, Fei Zheng, Jian-Ye Yang, Xia Kong, Yong-Zhang Huang, Shi-You Chen, Jia-Ning Wang Journal of Translational Medicine 2013, 11:113 (6 May 2013)

Abstract | Provisional PDF | PubMed

44.

446
Accesses

Research   Open Access

Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer

Satoshi Wada, Christopher M Jackson, Kiyoshi Yoshimura, Hung-Rong Yen, Derese Getnet, Timothy J Harris, Monica V Goldberg, Tullia C Bruno, Joseph F Grosso, Nicholas Durham, George J Netto, Drew M Pardoll, Charles G Drake Journal of Translational Medicine 2013, 11:89 (4 April 2013)

Abstract | Provisional PDF | PubMed

45.

443
Accesses

Review   Open Access Highly Accessed

Human conditions of insulin-like growth factor-I (IGF-I) deficiency

Juan E Puche, Inma Castilla-Cortázar Journal of Translational Medicine 2012, 10:224 (14 November 2012)

Abstract | Full text | PDF | PubMed

46.

442
Accesses

Research   Open Access Highly Accessed

Neural stem cell-like cells derived from autologous bone mesenchymal stem cells for the treatment of patients with cerebral palsy

Guojun Chen, Yali Wang, Zhenyu Xu, Feng Fang, Renmei Xu, Yue Wang, Xiaoli Hu, Lixing Fan, Houqi Liu Journal of Translational Medicine 2013, 11:21 (26 January 2013)

Abstract | Full text | PDF | PubMed

47.

432
Accesses

Research   Open Access

Intra-osseous injection of donor mesenchymal stem cell (MSC) into the bone marrow in living donor kidney transplantation; a pilot study

Hyunah Lee, Jae Berm Park, Sanghoon Lee, Soyoung Baek, HyunSoo Kim, Sung Joo Kim Journal of Translational Medicine 2013, 11:96 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

48.

432
Accesses

Research   Open Access

Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery

Delvin R Knight, Andrew H Smith, Richard L Schroeder, Chunli Huang, David A Beebe, Sharon A Sokolowski, Miao Wang Journal of Translational Medicine 2013, 11:101 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

49.

426
Accesses

Research   Open Access Highly Accessed

MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR

Annette Håvik, Petter Brandal, Hilde Honne, Hanne-Sofie Dahlback, David Scheie, Merete Hektoen, Torstein Meling, Eirik Helseth, Sverre Heim, Ragnhild A Lothe, Guro Lind Journal of Translational Medicine 2012, 10:36 (6 March 2012)

Abstract | Full text | PDF | PubMed

50.

411
Accesses

Review   Open Access Highly Accessed

HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future

Luciano Mariani, Aldo Venuti Journal of Translational Medicine 2010, 8:105 (27 October 2010)

Abstract | Full text | PDF | PubMed

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