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76.

324
Accesses

Review   Open Access

Use of V(D)J recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies

Federico Serana, Marco Chiarini, Cinzia Zanotti, Alessandra Sottini, Diego Bertoli, Andrea Bosio, Luigi Caimi, Luisa Imberti Journal of Translational Medicine 2013, 11:119 (9 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

77.

326
Accesses

Commentary   Open Access Highly Accessed

The site of origin of the 1918 influenza pandemic and its public health implications

John M Barry Journal of Translational Medicine 2004, 2:3 (20 January 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

314
Accesses

Research   Open Access

Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma

Tvrtko Hudolin, Zeljko Kastelan, Ivana Ilic, Katarina Levarda-Hudolin, Nikolina Basic-Jukic, Malte Rieken, Giulio C Spagnoli, Antonio Juretic, Chantal Mengus Journal of Translational Medicine 2013, 11:123 (16 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

79.

298
Accesses

Research   Open Access Highly Accessed

Calcium Sulfate and Platelet-Rich Plasma make a novel osteoinductive biomaterial for bone regeneration

Giuseppe Intini, Sebastiano Andreana, Francesco E Intini, Robert J Buhite, Libuse A Bobek Journal of Translational Medicine 2007, 5:13 (7 March 2007)

Abstract | Full text | PDF | PubMed

80.

291
Accesses

Review   Open Access Highly Accessed

Biomedical informatics and translational medicine

Indra Sarkar Journal of Translational Medicine 2010, 8:22 (26 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

81.

288
Accesses

Research   Open Access Highly Accessed

Mesenchymal stem cells and Interleukin-6 attenuate liver fibrosis in mice

Ghazanfar Ali Nasir, Sadia Mohsin, Mohsin Khan, Sulaiman Shams, Gibran Ali, Shaheen N Khan, Sheikh Riazuddin Journal of Translational Medicine 2013, 11:78 (26 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

82.

286
Accesses

Review   Open Access Highly Accessed

Lasers, stem cells, and COPD

Feng Lin, Steven F Josephs, Doru T Alexandrescu, Famela Ramos, Vladimir Bogin, Vincent Gammill, Constantin A Dasanu, Rosalia De Necochea-Campion, Amit N Patel, Ewa Carrier, David R Koos Journal of Translational Medicine 2010, 8:16 (16 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

285
Accesses

Research   Open Access Highly Accessed

Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda

Bhavana Prasher, Sapna Negi, Shilpi Aggarwal, Amit K Mandal, Tav P Sethi, Shailaja R Deshmukh, Sudha G Purohit, Shantanu Sengupta, Sangeeta Khanna, Farhan Mohammad, Gaurav Garg, Samir K Brahmachari, Indian Genome Variation Consortium, Mitali Mukerji Journal of Translational Medicine 2008, 6:48 (9 September 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Differences in genome wide expression levels and biochemical and hematological parameters have been demonstrated between the constitutional types fundamental to the practice of Ayurveda, an ancient Indian method of holistic health care.

84.

284
Accesses

Research   Open Access Highly Accessed

Differential sensitivity of melanoma cell lines with BRAF V600E mutation to the specific Raf inhibitor PLX4032

Jonas N Søndergaard, Ramin Nazarian, Qi Wang, Deliang Guo, Teli Hsueh, Stephen Mok, Hooman Sazegar, Laura E MacConaill, Jordi G Barretina, Sarah M Kehoe, Narsis Attar, Erika von Euw, Jonathan E Zuckerman, Bartosz Chmielowski, Begoña Comin-Anduix, Richard C Koya, Paul S Mischel, Roger S Lo, Antoni Ribas Journal of Translational Medicine 2010, 8:39 (20 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

85.

283
Accesses

Research   Open Access

Prevalence of KRAS, BRAF, and PIK3CA somatic mutations in patients with colorectal carcinoma may vary in the same population: clues from Sardinia

Grazia Palomba, Maria Colombino, Antonio Contu, Bruno Massidda, Giovanni Baldino, Antonio Pazzola, MariaTeresa Ionta, Francesca Capelli, Vittorio Trova, Tito Sedda, Giovanni Sanna, Francesco Tanda, Mario Budroni, Sardinian Translational Oncology Group (STOG), Giuseppe Palmieri, Antonio Cossu Journal of Translational Medicine 2012, 10:178 (29 August 2012)

Abstract | Full text | PDF | PubMed

86.

283
Accesses

Research   Open Access

The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation

Ling-juan Gao, Ping-qing Gu, Wei Zhao, Wen-yan Ding, Xue-qing Zhao, Shu-yu Guo, Tian-ying Zhong Journal of Translational Medicine 2013, 11:118 (8 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

87.

279
Accesses

Research   Open Access Highly Accessed

Neural stem cell-like cells derived from autologous bone mesenchymal stem cells for the treatment of patients with cerebral palsy

Guojun Chen, Yali Wang, Zhenyu Xu, Feng Fang, Renmei Xu, Yue Wang, Xiaoli Hu, Lixing Fan, Houqi Liu Journal of Translational Medicine 2013, 11:21 (26 January 2013)

Abstract | Full text | PDF | PubMed

88.

276
Accesses

Research   Open Access Highly Accessed

Endometrial regenerative cells: A novel stem cell population

Xiaolong Meng, Thomas E Ichim, Jie Zhong, Andrea Rogers, Zhenglian Yin, James Jackson, Hao Wang, Wei Ge, Vladimir Bogin, Kyle W Chan, Bernard Thébaud, Neil H Riordan Journal of Translational Medicine 2007, 5:57 (15 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The cells which thicken the womb wall during a woman’s menstrual cycle have similar properties to stem cells, and could be used in the treatment of damaged and/or old tissue.

89.

275
Accesses

Research   Open Access

Nuclear beta-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer

Xi-Qing Li, Xing-Long Yang, Gong Zhang, Si-Pei Wu, Xu-Bing Deng, Sheng-Jun Xiao, Qiu-Zhen Liu, Kai-Tai Yao, Guang-Hui Xiao Journal of Translational Medicine 2013, 11:114 (6 May 2013)

Abstract | Provisional PDF | PubMed

90.

273
Accesses

Protocol   Open Access Highly Accessed

Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)

Nishat Siddiqi, Margaret Bruce, Christopher J Neil, Baljit Jagpal, Graeme Maclennon, Seonaidh C Cotton, Sofia A Papadopoulo, Nicholas Bunce, Pitt Lim, Konstantin Schwarz, Satnam Singh, David Hildick-Smith, John D Horowitz, Melanie Madhani, Nicholas Boon, Juan-Carlos Kaski, Dana Dawson, Michael P Frenneaux Journal of Translational Medicine 2013, 11:116 (6 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

91.

273
Accesses

Review   Open Access

Immunity of human epithelial ovarian carcinoma: the paradigm of immune suppression in cancer

Vincent Lavoué, Aurélie Thédrez, Jean Levêque, Fabrice Foucher, Sébastien Henno, Vincent Jauffret, Marc-Antoine Belaud-Rotureau, Veronique Catros, Florian Cabillic Journal of Translational Medicine 2013, 11:147 (13 June 2013)

Abstract | Full text | PDF | PubMed

92.

270
Accesses

Review   Open Access Highly Accessed

Roles of microRNA on cancer cell metabolism

Bing Chen, Hongbin Li, Xiao Zeng, Pengbo Yang, Xinyu Liu, Xia Zhao, Shufang Liang Journal of Translational Medicine 2012, 10:228 (20 November 2012)

Abstract | Full text | PDF | PubMed

93.

268
Accesses

Review   Open Access Highly Accessed

Future research and therapeutic applications of human stem cells: general, regulatory, and bioethical aspects

Antonio Liras Journal of Translational Medicine 2010, 8:131 (10 December 2010)

Abstract | Full text | PDF | PubMed

94.

268
Accesses

Research   Open Access Highly Accessed

Hypoglycemic and beta cell protective effects of andrographolide analogue for diabetes treatment

Zaijun Zhang, Jie Jiang, Pei Yu, Xiangping Zeng, James W Larrick, Yuqiang Wang Journal of Translational Medicine 2009, 7:62 (16 July 2009)

Abstract | Full text | PDF | PubMed

95.

265
Accesses

Research   Open Access Highly Accessed

Identification and proteomic profiling of exosomes in human cerebrospinal fluid

Jonathan M Street, Perdita E Barran, C Logan Mackay, Stefan Weidt, Craig Balmforth, Tim S Walsh, Rod TA Chalmers, David J Webb, James W Dear Journal of Translational Medicine 2012, 10:5 (5 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

96.

260
Accesses

Research   Open Access

Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer

Satoshi Wada, Christopher M Jackson, Kiyoshi Yoshimura, Hung-Rong Yen, Derese Getnet, Timothy J Harris, Monica V Goldberg, Tullia C Bruno, Joseph F Grosso, Nicholas Durham, George J Netto, Drew M Pardoll, Charles G Drake Journal of Translational Medicine 2013, 11:89 (4 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

97.

261
Accesses

Research   Open Access

Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients

Maria Libera Ascierto, Michael O Idowu, Yingdong Zhao, Hanif Khalak, Kyle K Payne, Xiang-Yang Wang, Catherine I Dumur, Davide Bedognetti, Sara Tomei, Paolo A Ascierto, Anil Shanker, Harry D Bear, Ena Wang, Francesco M Marincola, Andrea De Maria, Masoud H Manjili Journal of Translational Medicine 2013, 11:145 (12 June 2013)

Abstract | Provisional PDF | PubMed

98.

255
Accesses

Research   Open Access

Stromal cell derived factor-1alpha protects stem cell derived insulin-producing cells from glucotoxicity under high glucose conditions in-vitro and ameliorates drug induced diabetes in rats

Muhammad Tariq, Muhammad Sharif Masoud, Azra Mehmood, Shaheen N Khan, Sheikh Riazuddin Journal of Translational Medicine 2013, 11:115 (6 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

99.

252
Accesses

Research   Open Access

Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis

Anne Sofie Siebuhr, Jianxia Wang, Morten Karsdal, Anne-C Bay-Jensen, Jin Y, Zheng Q Journal of Translational Medicine 2012, 10:195 (20 September 2012)

Abstract | Full text | PDF | PubMed

100.

250
Accesses

Research   Open Access

Translatability scoring in drug development: eight case studies

Alexandra Wendler, Martin Wehling Journal of Translational Medicine 2012, 10:39 (7 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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