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1: Mol Cell Biochem. 2000 Jan;204(1-2):135-55.
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N-myristoyltransferase.

Rajala RV, Datla RS, Moyana TN, Kakkar R, Carlsen SA, Sharma RK.

Department of Pathology and Saskatoon Cancer Centre, College of Medicine, Royal University Hospital, University of Saskatchewan, Canada.

Myristoylation refers to the co-translational addition of a myristoyl group to an amino-terminal glycine residue of a protein by an ubiquitously distributed enzyme myristoyl-CoA:protein N-myristoyltransferase (NMT, EC 2.3.1.97). This review describes the basic enzymology, molecular cloning and regulation of NMT activity in various pathophysiological processes such as colon cancer and diabetes.

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PMID: 10718634 [PubMed - indexed for MEDLINE]