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Cardiovascular, Metabolic and Lipoprotein Translation Section edited by Nehal N. Mehta

This section aims to speed mechanistic understanding, development of novel diagnostics and potential therapeutic targets within cardiovascular, metabolic diseases and lipoprotein diseases. The section is open to experiments involving cellular models, animal models, observational studies and clinical trials that are distinguished for their novelty in approach, design or indication, timeliness, and unique ability to translate laboratory concepts from the bench to the bedside.

Highest priority will be given to those manuscripts which are specifically focused on cardiovascular, metabolic and lipid disorders which enrich understanding of disease mechanism, novel therapeutics and state-of-the-art scientific technique.

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1.

Research   Open Access

Mild therapeutic hypothermia is superior to controlled normothermia for the maintenance of blood pressure and cerebral oxygenation, prevention of organ damage and suppression of oxidative stress after cardiac arrest in a porcine model

Petr Ostadal, Mikulas Mlcek, Andreas Kruger, Svatava Horakova, Marcela Skabradova, Frantisek Holy, Tomas Svoboda, Jan Belohlavek, Vladimir Hrachovina, Ludek Taborsky, Vlasta Dudkova, Hana Psotova, Otomar Kittnar, Petr Neuzil Journal of Translational Medicine 2013, 11:124 (20 May 2013)

Abstract | Provisional PDF | PubMed

2.

Protocol   Open Access Highly Accessed

Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)

Nishat Siddiqi, Margaret Bruce, Christopher J Neil, Baljit Jagpal, Graeme Maclennon, Seonaidh C Cotton, Sofia A Papadopoulo, Nicholas Bunce, Pitt Lim, Konstantin Schwarz, Satnam Singh, David Hildick-Smith, John D Horowitz, Melanie Madhani, Nicholas Boon, Juan-Carlos Kaski, Dana Dawson, Michael P Frenneaux Journal of Translational Medicine 2013, 11:116 (6 May 2013)

Abstract | Full text | PDF | PubMed

3.

Research   Open Access

PEP-1-CAT protects hypoxia/reoxygenation-induced cardiomyocyte apoptosis through multiple sigaling pathways

Lei Zhang, Shuang Wei, Jun-Ming Tang, Ling-Yun Guo, Fei Zheng, Jian-Ye Yang, Xia Kong, Yong-Zhang Huang, Shi-You Chen, Jia-Ning Wang Journal of Translational Medicine 2013, 11:113 (6 May 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Effects of age on noninvasive assessments of vascular function in nonhuman primates: implications for translational drug discovery

Delvin R Knight, Andrew H Smith, Richard L Schroeder, Chunli Huang, David A Beebe, Sharon A Sokolowski, Miao Wang Journal of Translational Medicine 2013, 11:101 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research   Open Access

Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios

Arduino A Mangoni, Angelo Zinellu, Ciriaco Carru, John R Attia, Marc McEvoy Journal of Translational Medicine 2013, 11:99 (15 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

Research   Open Access

Effects of sevoflurane postconditioning on cell death, inflammation and TLR expression in human endothelial cells exposed to LPS

Raquel Rodríguez-González, Aurora Baluja, Sonia Veiras Del Río, Alfonso Rodríguez, Jaime Rodríguez, Manuel Taboada, David Brea, Julián Álvarez Journal of Translational Medicine 2013, 11:87 (3 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

Research   Open Access Highly Accessed

Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies

Paulus Wohlfart, Wolfgang Linz, Thomas Hübschle, Dominik Linz, Jochen Huber, Sibylle Hess, Daniel Crowther, Ulrich Werner, Hartmut Ruetten Journal of Translational Medicine 2013, 11:84 (28 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

Research   Open Access

Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication

Prachi Gupta, Abhinav Kanwal, Uday Kumar Putcha, Yogesh Bulani, Bhavesh Sojitra, Tarak Nath Khatua, Madhusudana Kuncha, Sanjay Kumar Banerjee Journal of Translational Medicine 2013, 11:80 (26 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

Research   Open Access

Race and gender variation in response to evoked inflammation

Jane F Ferguson, Parth N Patel, Rhia Y Shah, Claire K Mulvey, Ram Gadi, Prabhjot S Nijjar, Haris M Usman, Nehal N Mehta, Rachana Shah, Stephen R Master, Kathleen J Propert, Muredach P Reilly Journal of Translational Medicine 2013, 11:63 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research   Open Access

Response of circulating heat shock protein 70 and anti-heat shock protein 70 antibodies to catheter ablation of atrial fibrillation

Jelena Kornej, Claudia Reinhardt, Jedrzej Kosiuk, Arash Arya, Gerhard Hindricks, Volker Adams, Daniela Husser, Andreas Bollmann Journal of Translational Medicine 2013, 11:49 (23 February 2013)

Abstract | Full text | PDF | PubMed

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