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Immunobiology and immunotherapy section Section edited by Adrian Bot

This section aims to enrich the communication between basic biological and immunological sciences and the clinical investigation arena.

As immunology has evolved to be a central discipline connected to a wide range of therapeutic areas, the number and diversity of platform technologies has also increased, spanning small molecules, biologics, microbial vectors and cells. Such levels of activity require appropriate means to share new knowledge and to catalyze the development of the field. This section aims to provide such a platform and welcomes submissions across all disciplines, including inflammation, autoimmunity, transplantation, metabolic disorders.

The section was founded with the Society for Immunotherapy of Cancer (SITC) under the title "Tumor immunology and biological cancer therapy" and Edited by Pedro Romero.

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1.

Research   Open Access

Immunohistochemical analysis of the expression of MAGE-A and NY-ESO-1 cancer/testis antigens in diffuse large B-cell testicular lymphoma

Tvrtko Hudolin, Zeljko Kastelan, Ivana Ilic, Katarina Levarda-Hudolin, Nikolina Basic-Jukic, Malte Rieken, Giulio C Spagnoli, Antonio Juretic, Chantal Mengus Journal of Translational Medicine 2013, 11:123 (16 May 2013)

Abstract | Provisional PDF | PubMed

2.

Research   Open Access

The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-alpha production

Stefania Laurent, Paola Queirolo, Silvia Boero, Sandra Salvi, Patrizia Piccioli, Simona Boccardo, Simona Minghelli, Anna Morabito, Vincenzo Fontana, Gabriella Pietra, Paolo Carrega, Nicoletta Ferrari, Francesca Tosetti, Lung-Ji Chang, Maria Cristina Mingari, Guido Ferlazzo, Alessandro Poggi, Maria Pia Pistillo Journal of Translational Medicine 2013, 11:108 (1 May 2013)

Abstract | Provisional PDF | PubMed

3.

Research   Open Access

Treatment of malignant effusion by oncolytic virotherapy in an experimental subcutaneous xenograft model of lung cancer

Stephanie Weibel, Elisabeth Hofmann, Thomas Christian Basse-Luesebrink, Ulrike Donat, Carolin Seubert, Marion Adelfinger, Prisca Gnamlin, Christina Kober, Alexa Frentzen, Ivaylo Gentschev, Peter Michael Jakob, Aladar A Szalay Journal of Translational Medicine 2013, 11:106 (1 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

4.

Research   Open Access Highly Accessed

Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer

Hiroyuki Suzuki, Mitsuro Fukuhara, Takumi Yamaura, Satoshi Mutoh, Naoyuki Okabe, Hiroshi Yaginuma, Takeo Hasegawa, Atsushi Yonechi, Jun Osugi, Mika Hoshino, Takashi Kimura, Mitsunori Higuchi, Yutaka Shio, Kazuya Ise, Kazuyoshi Takeda, Mitsukazu Gotoh Journal of Translational Medicine 2013, 11:97 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

5.

Research   Open Access

Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer

Satoshi Wada, Christopher M Jackson, Kiyoshi Yoshimura, Hung-Rong Yen, Derese Getnet, Timothy J Harris, Monica V Goldberg, Tullia C Bruno, Joseph F Grosso, Nicholas Durham, George J Netto, Drew M Pardoll, Charles G Drake Journal of Translational Medicine 2013, 11:89 (4 April 2013)

Abstract | Provisional PDF | PubMed

6.

Review   Open Access Highly Accessed

Cytokine-induced killer cells promote antitumor immunity

Jingting Jiang, Changping Wu, Binfeng Lu Journal of Translational Medicine 2013, 11:83 (28 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

Research   Open Access Highly Accessed

Growth inhibition of different human colorectal cancer xenografts after a single intravenous injection of oncolytic vaccinia virus GLV-1h68

Klaas Ehrig, Mehmet O Kilinc, Nanhai G Chen, Jochen Stritzker, Lisa Buckel, Qian Zhang, Aladar A Szalay Journal of Translational Medicine 2013, 11:79 (26 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

Research   Open Access

Dynamically expressed microRNA-15b modulates the activities of CD8+ T lymphocytes in mice with Lewis lung carcinoma

Guocheng Zhong, Xiaoming Cheng, Haixia Long, Luhang He, Wei Qi, Tong Xiang, Zhongquan Zhao, Bo Zhu Journal of Translational Medicine 2013, 11:71 (21 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

9.

Research   Open Access

Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model

Gregory T Wurz, Audrey M Gutierrez, Brittany E Greenberg, Daniel P Vang, Stephen M Griffey, Chiao-Jung Kao, Michael Wolf, Michael W DeGregorio Journal of Translational Medicine 2013, 11:64 (13 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

10.

Research   Open Access

Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor

Steven C Katz, Rachel A Burga, Seema Naheed, Lauren A Licata, Mitchell Thorn, Doreen Osgood, Cang T Nguyen, N Joseph Espat, Jonathan A Fletcher, Richard P Junghans Journal of Translational Medicine 2013, 11:46 (21 February 2013)

Abstract | Full text | PDF | PubMed

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