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Personalized medicine Section edited by Lotfi Chouchane (Qatar Foundation, Weill Cornell Medical College)

This section aims to provide a platform for research that will revolutionize patient care through the use of novel molecular predisposing screening, diagnostic, prognostic and pharmacogenomics. Advances in human genome research are opening the door to a new paradigm for practicing medicine that promises to transform healthcare. Personalized medicine will impact the way that medicine is practiced.

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1.

Research   Open Access

Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians

Jingxuan Shan, Khalid Al-Rumaihi, Danny Rabah, Issam Al-Bozom, Dhanya Kizhakayil, Karim Farhat, Sami Al-Said, Hala Kfoury, Shoba P Dsouza, Jillian Rowe, Hanif G Khalak, Shahzad Jafri, Idil I Aigha, Lotfi Chouchane Journal of Translational Medicine 2013, 11:121 (13 May 2013)

Abstract | Full text | PDF | PubMed

2.

Research   Open Access

High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFR

Fang Wang, Sha Fu, Qiong Shao, Yan-Bin Zhou, Xiao Zhang, Xu Zhang, Cong Xue, Jian-Guang Lin, Li-Xia Huang, Li Zhang, Wei-Min Zhang, Jian-Yong Shao Journal of Translational Medicine 2013, 11:90 (4 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

Research   Open Access

SSX2IP promotes metastasis and chemotherapeutic resistance of hepatocellular carcinoma

Pu Li, Ying Lin, Yu Zhang, Zhenggang Zhu, Keke Huo Journal of Translational Medicine 2013, 11:52 (1 March 2013)

Abstract | Full text | PDF | PubMed

4.

Research   Open Access

Prothrombotic gene variants as risk factors of acute myocardial infarction in young women

Rossella Tomaiuolo, Chiara Bellia, Antonietta Caruso, Rosanna Di Fiore, Sandro Quaranta, Davide Noto, Angelo B Cefalù, Pierpaolo Di Micco, Federica Zarrilli, Giuseppe Castaldo, Maurizio R Averna, Marcello Ciaccio Journal of Translational Medicine 2012, 10:235 (21 November 2012)

Abstract | Full text | PDF | PubMed

5.

Research   Open Access

Identification of SLC26A4 c.919-2A>G compound heterozygosity in hearing-impaired patients to improve genetic counseling

Qi Li, Qing-wen Zhu, Yong-yi Yuan, Sha-sha Huang, Dong-yi Han, De-liang Huang, Pu Dai Journal of Translational Medicine 2012, 10:225 (14 November 2012)

Abstract | Full text | PDF | PubMed

6.

Research   Open Access

A gender-related action of IFNbeta-therapy was found in multiple sclerosis

Ida Contasta, Rocco Totaro, Patrizia Pellegrini, Tiziana Del Beato, Antonio Carolei, Anna Maria Berghella Journal of Translational Medicine 2012, 10:223 (14 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

7.

Research   Open Access Highly Accessed

Prognostic and predictive value of circulating tumor cell analysis in colorectal cancer patients

Andreia de Albuquerque, Ilja Kubisch, Ulrich Stölzel, Dominikus Ernst, Joachim Boese-Landgraf, Georg Breier, Gudrun Stamminger, Nikos Fersis, Sepp Kaul Journal of Translational Medicine 2012, 10:222 (13 November 2012)

Abstract | Full text | PDF | PubMed

8.

Review   Open Access

Future detection and monitoring of diabetes may entail analysis of both β-cell function and volume: How markers of β-cell loss may assist

Anita V Neutzsky-Wulff, Kim V Andreassen, Sara T Hjuler, Michael Feigh, Anne-Christine Bay-Jensen, Qinlong Zheng, Kim Henriksen, Morten A Karsdal Journal of Translational Medicine 2012, 10:214 (30 October 2012)

Abstract | Full text | PDF | PubMed

9.

Research   Open Access

Five novel glucose-6-phosphate dehydrogenase deficiency haplotypes correlating with disease severity

Ashraf Dallol, Huda Banni, Mamdooh A Gari, Mohammed H Al-Qahtani, Adel M Abuzenadeh, Fatin Al-Sayes, Adeel G Chaudhary, Jeffrey Bidwell, Wael Kafienah Journal of Translational Medicine 2012, 10:199 (24 September 2012)

Abstract | Full text | PDF | PubMed

10.

Research   Open Access

Preoperative Cyfra21-1 and SCC-Ag serum titers predict survival in patients with stage II esophageal squamous cell carcinoma

Xun Cao, Lin Zhang, Gui-Rong Feng, Juan Yang, Ruo-Yan Wang, Jun Li, Xiao-Min Zheng, Yu-Jing Han Journal of Translational Medicine 2012, 10:197 (21 September 2012)

Abstract | Full text | PDF | PubMed

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