Thematic Series

Tumor Immunology and Biological Cancer Therapy

Edited by iSBTc (Pedro Romero)

The Tumor Immunology and Biological Cancer Therapy section of Journal of Translational Medicine aims to enrich the communication between basic biological and immunological sciences and the clinical investigation arena. The section is supported and edited by the International Society for Biological Therapy of Cancer. For further information please see the journal’s ‘About’ page.

Research

Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-alpha 2b treatment
Paolo A Ascierto, Maria Napolitano, Egidio Celentano, Ester Simeone, Giusy Gentilcore, Antonio Daponte, Mariaelena Capone, Corrado Caraco, Rosa Calemma, Gerardo Beneduce, Margherita Cerrone, Vincenzo De Rosa, Giuseppe Palmieri, Giuseppe Castello, John M Kirkwood, Francesco M Marincola, Nicola Mozzillo
Journal of Translational Medicine 2010, 8:76 (16 August 2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Commentary

Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies
Richard Paul Junghans
Journal of Translational Medicine 2010, 8:55 (10 June 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial
Håkan Norell, Isabel Poschke, Jehad Charo, Wei Z Wei, Courtney Erskine, Marie P Piechocki, Keith L Knutson, Jonas Bergh, Elisabet Lidbrink, Rolf Kiessling
Journal of Translational Medicine 2010, 8:53 (7 June 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Review

An integrative paradigm to impart quality to correlative science
Michael Kalos
Journal of Translational Medicine 2010, 8:26 (16 March 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy
Kotaro Sasaki, Gary Kohanbash, Aki Hoji, Ryo Ueda, Heather A McDonald, Todd A Reinhart, Jeremy Martinson, Michael T Lotze, Francesco M Marincola, Ena Wang, Mitsugu Fujita, Hideho Okada
Journal of Translational Medicine 2010, 8:17 (18 February 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma
Omar Eton, Merrick I Ross, Mary Jo East, Paul F Mansfield, Nicholas Papadopoulos, Julie A Ellerhorst, Agop Y Bedikian, Jeffrey E Lee
Journal of Translational Medicine 2010, 8:9 (29 January 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma
Osama E Rahma, Ed Ashtar, Ramy Ibrahim, Antoun Toubaji, Barry Gause, Vincent E Herrin, W Marston Linehan, Seth M Steinberg, Frank Grollman, George Grimes, Sarah A Bernstein, Jay A Berzofsky, Samir N Khleif
Journal of Translational Medicine 2010, 8:8 (28 January 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Boosting high-intensity focused ultrasound-induced anti-tumor immunity using a sparse-scan strategy that can more effectively promote dendritic cell maturation
Fang Liu, Zhenlin Hu, Lei Qiu, Chun Hui, Chao Li, Pei Zhong, Junping Zhang
Journal of Translational Medicine 2010, 8:7 (27 January 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Mutation or loss of Wilms' tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination
Antonia Busse, Anne Letsch, Carmen Scheibenbogen, Anika Nonnenmacher, Sebastian Ochsenreither, Eckhard Thiel, Ulrich Keilholz
Journal of Translational Medicine 2010, 8:5 (21 January 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Molecular signatures of maturing dendritic cells: implications for testing the quality of dendritic cell therapies
Ping Jin, Tae Hee Han, Jiaqiang Ren, Stefanie Saunders, Ena Wang, Francesco M Marincola, David F Stroncek
Journal of Translational Medicine 2010, 8:4 (15 January 2010)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Increased immunogenicity of surviving tumor cells enables cooperation between liposomal doxorubicin and IL-18
Ioannis Alagkiozidis, Andrea Facciabene, Carmine Carpenito, Fabian Benencia, Zdenka Jonak, Sarah Adams, Richard G Carroll, Phyllis A Gimotty, Rachel Hammond, Gwen-äel Danet-Desnoyers, Carl H June, Daniel J Powell Jr, George Coukos
Journal of Translational Medicine 2009, 7:104 (10 December 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Research

Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation
Erica L Carpenter, Rosemarie Mick, Jens Rüter, Robert H Vonderheide
Journal of Translational Medicine 2009, 7:93 (11 November 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

Editorial

Announcing the Tumor Immunology and Biological Cancer Therapy section (edited by iSBTc) of the Journal of Translational Medicine
Pedro Romero, Bernard A Fox, iSBTc Executive Office
Journal of Translational Medicine 2009, 7:80 (17 September 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]

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